Artorix 120 mg (Tablet)

Unit Price: ৳ 14.00 (20's pack: ৳ 280.00)

Medicine Details

Indications

  • Osteoarthritis (OA)
  • Rheumatoid arthritis (RA)
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Symptomatic Relief

1

Function

  • Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
  • Reduction of pain, inflammation, and fever
  • Short-term treatment of moderate pain
  • Decreased potential for gastric toxicity
  • Decreased effects on platelet aggregation

Dosage

  • Osteoarthritis: 30 mg once daily, increased to 60 mg if necessary
  • Rheumatoid arthritis: 90 mg once daily
  • Ankylosing spondylitis: 90 mg once daily
  • Acute gouty arthritis: 120 mg once daily for 8 days
  • Postoperative dental surgery pain: 90 mg once daily, maximum of 3 days

Interaction

  • Medicine:
    • Oral anticoagulants
    • Diuretics, ACE inhibitors and Angiotensin II Antagonists
    • Acetylsalicylic Acid
    • Ciclosporin and tacrolimus
    • Lithium
  • Food & Others: Take without regards to meals

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or GI bleeding
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Appetite and weight change
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Impaired mental acuity
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia
  • Arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Not recommended for breastfeeding

Precautions & Warnings

  • Caution in patients at risk of GI complications
  • Consideration for patients with significant cardiovascular risk factors
  • Monitoring of renal function
  • Exercise caution in patients with cardiac failure, left ventricular dysfunction, or hypertension
  • Monitoring liver function if signs of hepatic insufficiency occur
  • Discontinue at first appearance of hypersensitivity
  • May mask fever and other signs of inflammation
  • Caution when co-administering with warfarin or other oral anticoagulants

Overdose Effects

Did not result in significant toxicity up to 150 mg/day

Therapeutic Class

Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Below 30°C, protect from light & moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg

Common Questions

  • What is Artorix 120 mg Tablet?: Selective COX-2 inhibitor
  • Uses:
    • Symptomatic relief of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis
  • Duration of effect: 20-24 hours
  • Onset of action: 1-2 hours, faster if taken without food
  • Pregnancy warnings: Not recommended
  • Habit forming: No habit forming tendencies reported
  • Breast-feeding warnings: Not recommended

Quick Tips

  • Relieves pain and inflammation
  • May cause fewer stomach problems compared to other NSAIDs
  • May cause dizziness and fatigue, avoid driving
  • Avoid alcohol consumption
  • Monitor blood pressure regularly
  • Inform doctor of medical history
  • Regular blood tests for liver function during long-term use
  • Not to be taken during pregnancy, planning to conceive, or breastfeeding

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