Asixone 1 gm/vial (IV Injection)

1 gm vial: ৳ 190.00

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • 3rd generation broad-spectrum parenteral cephalosporin antibiotic
  • Potent bactericidal activity
  • Interferes with bacterial cell wall synthesis
  • Stable in the presence of beta lactamases
  • Long plasma elimination half-life of 6 to 9 hours
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Adult dosage: 1 to 2 gm by intravenous or intramuscular administration
  • Dosage for different infections specified
  • Maximum dose: 4 gm/day
  • Duration of therapy: 4 to 14 days

Administration

  • Instructions for preparation of solutions for intramuscular/intravenous injections
  • Recommended concentrations for injection
  • Test dose for patient tolerance
  • Duration of solution potency at different temperatures

Interaction

  • No reported drug interactions

Contraindications

  • Not to be given to patients with hypersensitivity to cephalosporin antibiotics

Side Effects

  • Range of possible side effects specified
  • Rare occurrence of local phlebitis post intravenous administration

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution advised during lactation

Precautions & Warnings

  • Risk of anaphylactic shock
  • Monitoring gallbladder for sludge formation
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

  • Not recommended for neonates if premature and newborn

Overdose Effects

  • No specific antidote
  • Symptomatic treatment recommended

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store vial below 30°C, away from light & moisture
  • Keep out of the reach of children

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