Asixone 500 mg/vial (IV Injection)
500 mg vial: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Asiatic laboratories ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum cephalosporin antibiotic
- Bactericidal activity against Gram-positive and Gram-negative organisms
- Interferes with bacterial cell wall synthesis
- Stable in the presence of beta lactamases
- Long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Highly protein bound (95%)
Dosage
- Usual adult dose of 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose of 4 gm/day for certain infections
- Usual pediatric dose of 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Duration of therapy: 4 to 14 days
Administration
- Preparation of solutions for intramuscular / intravenous injections
- Administered over 2-4 minutes by intramuscular or intravenous injection
- Test dose for patient tolerance
- Reconstituted solution potency of at least 6 hours at room temperature
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution in lactating mothers due to low excretion in human milk
Precautions & Warnings
- Risk of anaphylactic shock
- Possibility of gallbladder sludge with prolonged therapy
- Regular blood picture checks during prolonged treatment
Use in Special Populations
- Avoid in premature neonates and newborns up to 28 days of age
Overdose Effects
- No specific antidote
- Symptomatic treatment for overdosage
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place below 30°C
- Keep away from light and moisture
- Keep out of the reach of children