Asizime 500 mg/vial (IV Infusion)
500 mg vial: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Asiatic laboratories ltd |
| Also available as |
Title
- Asizime 500mg/vial Injection
Categories
- Medicine
- Pharmaceuticals
Description
- Asizime is indicated for infections in lower respiratory and upper respiratory tract, otitis media, skin and soft tissue infections, and sexually transmitted diseases in men and women.
- Azithromycin, the active ingredient in Asizime, is acid-stable and can be taken orally with no need of protection from gastric acids.
- Azizime can be administered orally or through intravenous (IV) infusion.
Dimensions
- N/A
Color Options
- N/A
Functions
- Treatment of lower respiratory tract infections
- Treatment of upper respiratory tract infections
- Treatment of otitis media
- Treatment of skin and soft tissue infections
- Treatment of sexually transmitted diseases
- Prevention of community-acquired pneumonia
- Prevention of pharyngitis/tonsillitis
Materials
- Azithromycin
Technical Specifications
- 500mg/vial dosage for adult oral administration
- Dosage varies for children based on body weight
- Dosage is different for treatment of sexually transmitted diseases and typhoid fever
Design Elements
- Suspension reconstitution procedure
- Oral administration at least 1 hour before or 2 hours after meal
- Intravenous therapy with switch to oral therapy as per clinical response
Usability Features
- Well-tolerated with a low incidence of side-effects
- No effect on a patient’s ability to drive or operate machinery
Indications
- Infections in lower respiratory tract including bronchitis and pneumonia
- Infections in upper respiratory tract including sinusitis and pharyngitis/tonsillitis
- Otitis media
- Skin and soft tissue infections
- Sexually transmitted diseases in men and women including non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis
Mode of Action
- Azithromycin's half-life allows a large single dose to be administered and maintain bacteriostatic levels in the infected tissue for several days
- Actively transported to the site of infection due to high concentration in phagocytes
- Acts by binding to the 50S ribosomal subunit of susceptible microorganisms, interfering with microbial protein synthesis
Dosage
- 500mg once daily orally for 3 days for adult
- 250mg once daily orally for 4 days for adult
- Doses based on body weight for children over 6 months
- 500mg IV infusion for adult patients with community-acquired pneumonia
- 500mg IV infusion for adult patients with pelvic inflammatory disease
Administration
- Suspension reconstitution process
- Oral administration at specific timings
- Intravenous therapy followed by oral route for completing therapy
Interaction
- Instructions for co-administration with antacids, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, terfenadine
Contraindications
- Hypersensitivity to Azithromycin or any other macrolide antibiotic
- Co-administration of ergot derivatives
- Patients with hepatic diseases
Side Effects
- Mild to moderate gastrointestinal side-effects
- Allergic reactions including rash and photosensitivity
- Reversible elevations in liver transaminases
- Rare instances of cholestatic jaundice and transient mild reductions in neutrofil counts
- Rare cases of reversible hearing impairment in investigational studies
Pregnancy & Lactation
- Pregnancy Category B
- No well controlled studies in pregnant women
- Caution for use during pregnancy and lactation
Precautions & Warnings
- Rare serious allergic reactions reported
Use in Special Populations
- No dose adjustment needed in patients with mild renal impairment
- Caution in using in patients with severe renal impairment
- Not recommended for patients with hepatic disease
- No evidence of effect on driving or using machinery
Overdose Effects
- Typical symptoms include hearing loss, severe nausea, vomiting, and diarrhea
- General supportive measures indicated in case of overdosage
Storage Conditions
- Keep in a dry place, away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C38H72N2O12
- Chemical Structure Image: (URL)
Commonly Asked Questions
- Description of Asizime 500 mg/vial IV Infusion
- Uses of Asizime 500 mg/vial IV Infusion
- Side Effects of Asizime 500 mg/vial IV Infusion
- Instructions for storage and disposal of Asizime 500 mg/vial IV Infusion
- Possibility of causing diarrhea
- Safety of Asizime 500 mg/vial IV Infusion
- Asizime 500 mg/vial IV Infusion as an antibiotic
- Actions to take if no improvement is noticed after taking Asizime 500 mg/vial IV Infusion
- Quick Tips for taking Asizime 500 mg/vial IV Infusion