Asizime 500 mg/vial (IV Infusion)

500 mg vial: ৳ 130.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Asiatic laboratories ltd
Also available as
Asizith 250 mg tablet Asizith 500 mg tablet Asizith 200 mg suspension Asizime 1 gm injection Asizime 250 mg injection

Title

  • Asizime 500mg/vial Injection

Categories

  • Medicine
  • Pharmaceuticals

Description

  • Asizime is indicated for infections in lower respiratory and upper respiratory tract, otitis media, skin and soft tissue infections, and sexually transmitted diseases in men and women.
  • Azithromycin, the active ingredient in Asizime, is acid-stable and can be taken orally with no need of protection from gastric acids.
  • Azizime can be administered orally or through intravenous (IV) infusion.

Dimensions

  • N/A

Color Options

  • N/A

Functions

  • Treatment of lower respiratory tract infections
  • Treatment of upper respiratory tract infections
  • Treatment of otitis media
  • Treatment of skin and soft tissue infections
  • Treatment of sexually transmitted diseases
  • Prevention of community-acquired pneumonia
  • Prevention of pharyngitis/tonsillitis

Materials

  • Azithromycin

Technical Specifications

  • 500mg/vial dosage for adult oral administration
  • Dosage varies for children based on body weight
  • Dosage is different for treatment of sexually transmitted diseases and typhoid fever

Design Elements

  • Suspension reconstitution procedure
  • Oral administration at least 1 hour before or 2 hours after meal
  • Intravenous therapy with switch to oral therapy as per clinical response

Usability Features

  • Well-tolerated with a low incidence of side-effects
  • No effect on a patient’s ability to drive or operate machinery

Indications

  • Infections in lower respiratory tract including bronchitis and pneumonia
  • Infections in upper respiratory tract including sinusitis and pharyngitis/tonsillitis
  • Otitis media
  • Skin and soft tissue infections
  • Sexually transmitted diseases in men and women including non-gonococcal urethritis and cervicitis due to Chlamydia trachomatis

Mode of Action

  • Azithromycin's half-life allows a large single dose to be administered and maintain bacteriostatic levels in the infected tissue for several days
  • Actively transported to the site of infection due to high concentration in phagocytes
  • Acts by binding to the 50S ribosomal subunit of susceptible microorganisms, interfering with microbial protein synthesis

Dosage

  • 500mg once daily orally for 3 days for adult
  • 250mg once daily orally for 4 days for adult
  • Doses based on body weight for children over 6 months
  • 500mg IV infusion for adult patients with community-acquired pneumonia
  • 500mg IV infusion for adult patients with pelvic inflammatory disease

Administration

  • Suspension reconstitution process
  • Oral administration at specific timings
  • Intravenous therapy followed by oral route for completing therapy

Interaction

  • Instructions for co-administration with antacids, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, terfenadine

Contraindications

  • Hypersensitivity to Azithromycin or any other macrolide antibiotic
  • Co-administration of ergot derivatives
  • Patients with hepatic diseases

Side Effects

  • Mild to moderate gastrointestinal side-effects
  • Allergic reactions including rash and photosensitivity
  • Reversible elevations in liver transaminases
  • Rare instances of cholestatic jaundice and transient mild reductions in neutrofil counts
  • Rare cases of reversible hearing impairment in investigational studies

Pregnancy & Lactation

  • Pregnancy Category B
  • No well controlled studies in pregnant women
  • Caution for use during pregnancy and lactation

Precautions & Warnings

  • Rare serious allergic reactions reported

Use in Special Populations

  • No dose adjustment needed in patients with mild renal impairment
  • Caution in using in patients with severe renal impairment
  • Not recommended for patients with hepatic disease
  • No evidence of effect on driving or using machinery

Overdose Effects

  • Typical symptoms include hearing loss, severe nausea, vomiting, and diarrhea
  • General supportive measures indicated in case of overdosage

Storage Conditions

  • Keep in a dry place, away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C38H72N2O12
  • Chemical Structure Image: (URL)

Commonly Asked Questions

  • Description of Asizime 500 mg/vial IV Infusion
  • Uses of Asizime 500 mg/vial IV Infusion
  • Side Effects of Asizime 500 mg/vial IV Infusion
  • Instructions for storage and disposal of Asizime 500 mg/vial IV Infusion
  • Possibility of causing diarrhea
  • Safety of Asizime 500 mg/vial IV Infusion
  • Asizime 500 mg/vial IV Infusion as an antibiotic
  • Actions to take if no improvement is noticed after taking Asizime 500 mg/vial IV Infusion
  • Quick Tips for taking Asizime 500 mg/vial IV Infusion

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