Herculix 500 mg/vial (IM Injection)

500 mg vial: ৳ 150.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Kumudini pharma ltd
Also available as
Herculix 500 mg injection Herculix 1 gm injection Herculix 1 gm injection Herculix 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic. It has potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms.

Dosage

  • Adult: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Infants and Children: 50 to 75 mg/kg intravenous or intramuscular administration once a day

Administration

  • Intramuscular Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in 2 ml Lidocaine HCI 1% injection or 1 g Ceftriaxone in 3.5 ml of Lidocaine HCI 1% injection
  • Intravenous Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in 5 ml of Water for injection or 1 g Ceftriaxone in 10 ml of Water for injection USP or 2 g Ceftriaxone in 20 ml of Water for injection

Interaction

No drug interactions have been reported

Contraindications

Ceftriaxone should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea and vomiting
  • Cutaneous reactions including rash, pruritus, urticaria
  • Hematologic reactions including eosinophilia, thrombocytopenia
  • Hepatic reactions including elevations of SGOT or SGPT
  • CNS reactions including nervousness, confusion, sleep disturbances

Pregnancy & Lactation

Its safety in human pregnancy has not been established

Precautions & Warnings

  • Anaphylactic shock cannot be ruled out
  • During prolonged treatment the blood picture should be checked at regular intervals

Use in Special Populations

Herculix must not be given to neonates if premature and newborn

Overdose Effects

There is no specific antidote. Treatment of overdosage should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Vial should be stored in a cool, dry place (below 30°C), away from light & moisture

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