Herculix 1 gm/vial (IV Injection)
1 gm vial: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Kumudini pharma ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
- Interferes with the synthesis of the bacterial cell wall
- High stability in the presence of beta lactamases
- Relatively long plasma elimination half-life of about 6 to 9 hours
- Not metabolized in the body
- Highly protein bound (95%)
- Excretion in urine and feces
Dosage
- Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
- Doses for specific infections and patient age groups
- Duration of therapy: continue for more than 2 days after signs and symptoms of infection have disappeared
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections
- Different dissolution requirements for intramuscular and intravenous injection
- Administration over 2-4 minutes for intramuscular or intravenous injection, or over a period of 30 minutes for tubing infusion
- Patient tolerance test recommended
Interaction
No drug interactions reported
Contraindications
Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution during lactation
Precautions & Warnings
- Risk of anaphylactic shock
- Potential gallbladder sludge
- Regular blood picture checks during prolonged treatment
Use in Special Populations
Not recommended for neonates if premature and newborn (up to 28 days of age)
Overdose Effects
No specific antidote; symptomatic treatment
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Store in a cool, dry place (below 30°C), away from light & moisture; keep out of reach of children