Herculix 1 gm/vial (IV Injection)

1 gm vial: ৳ 200.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Kumudini pharma ltd
Also available as
Herculix 500 mg injection Herculix 500 mg injection Herculix 1 gm injection Herculix 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
  • Interferes with the synthesis of the bacterial cell wall
  • High stability in the presence of beta lactamases
  • Relatively long plasma elimination half-life of about 6 to 9 hours
  • Not metabolized in the body
  • Highly protein bound (95%)
  • Excretion in urine and feces

Dosage

  • Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
  • Doses for specific infections and patient age groups
  • Duration of therapy: continue for more than 2 days after signs and symptoms of infection have disappeared

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Different dissolution requirements for intramuscular and intravenous injection
  • Administration over 2-4 minutes for intramuscular or intravenous injection, or over a period of 30 minutes for tubing infusion
  • Patient tolerance test recommended

Interaction

No drug interactions reported

Contraindications

Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution during lactation

Precautions & Warnings

  • Risk of anaphylactic shock
  • Potential gallbladder sludge
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

Not recommended for neonates if premature and newborn (up to 28 days of age)

Overdose Effects

No specific antidote; symptomatic treatment

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture; keep out of reach of children

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