Herculix 2 gm/vial (IV Injection)
2 gm vial: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Kumudini pharma ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic.
Mode of Action
Interferes with the synthesis of the bacterial cell wall.
Dosage
- Adult:
- 1 to 2 gm by intravenous or intramuscular administration once a day
- 1 to 2 g IV or IM once a day (or in equally divided doses twice a day) for various conditions
- 250 mg IM as a single dose for uncomplicated gonococcal infections
- 1 g IV as a single dose 30 to 120 minutes before surgery for surgical prophylaxis
- Infants and Children (01 month or older):
- 50 to 75 mg/kg intravenous or intramuscular administration once a day
- 50 to 75 mg/kg IV or IM once a day (or in equally divided doses twice a day) for various conditions
- Duration of therapy: Continue for more than 2 days after signs and symptoms of infection have disappeared. Usual duration is 4 to 14 days; in complicated infections, longer therapy may be required.
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections:
- For Intramuscular Injection: Dissolve in Lidocaine HCI 1% injection
- For Intravenous Injection: Dissolve in Water for injection
- The injection should be administered over 2-4 minutes
Interaction
No drug interactions reported.
Contraindications
Not for patients with a history of hypersensitivity to cephalosporin antibiotics.
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis following intravenous administration
Pregnancy & Lactation
Safety in human pregnancy not established. Caution during lactation.
Precautions & Warnings
- Anaphylactic shock
- Shadows suggesting sludge in gallbladder
- Regular blood picture checking during prolonged treatment
Use in Special Populations
Not for neonates if premature and newborn
Overdose Effects
No specific antidote. Treatment should be symptomatic.
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Store in a cool, dry place (below 30° C), away from light and moisture. Keep out of the reach of children.