Itrafun 100 mg (Capsule)

Unit Price: ৳ 15.00 (5 x 6: ৳ 450.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Itraconazole
Company Kumudini pharma ltd

Indications

  • Treatment of oropharyngeal candidiasis
  • Treatment of vulvovaginal candidiasis
  • Treatment of pityriasis versicolor
  • Treatment of tinea pedis
  • Treatment of tinea cruris
  • Treatment of tinea corporis
  • Treatment of tinea manuum
  • Treatment of onychomycosis
  • Treatment of histoplasmosis
  • Treatment of systemic candidiasis
  • Treatment of aspergillosis
  • Treatment of cryptococcosis
  • Maintenance therapy in AIDS patients
  • Prevention of fungal infection during prolonged neutropenia

Pharmacology

  • Inhibition of Cytochrome P-450 dependent enzymes
  • Impairment of ergosterol biosynthesis in yeast and fungal cells
  • Abnormalities in permeability
  • Abnormal cell wall formation
  • Accumulation of intracellular lipids
  • Membrane bound enzyme activity

Dosage & Administration

  • 100 & 200 mg preparation
  • 65 mg & 130 mg preparation
  • Varied dosage based on specific conditions
  • Oral administration
  • Dose adjustment based on clinical response

Interaction

  • Interactions with terfenadine
  • Interactions with astemizole
  • Interactions with cisapride
  • Interactions with HMG-CoA reductase inhibitors
  • Interactions with rifampin
  • Interactions with phenytoin
  • Interactions with phenobarbital
  • Interactions with digoxin
  • Interactions with calcium channel blockers

Contraindications

  • Known hypersensitivity to the drug
  • Severe hepatic disease
  • Concomitant use with rifampin

Side Effects

  • Nausea
  • Abdominal pain
  • Dyspepsia
  • Constipation
  • Headache
  • Dizziness
  • Raised liver enzymes
  • Menstrual disorders
  • Allergic reactions
  • Hepatitis and cholestatic jaundice
  • Peripheral neuropathy
  • Stevens-Johnson syndrome
  • Hypokalaemia
  • Oedema
  • Hair loss

Pregnancy & Lactation

  • Contraindicated in pregnancy
  • Not recommended during breastfeeding

Precautions & Warnings

  • Impaired absorption with reduced gastric acidity
  • Administration with acid neutralizing medicines
  • Administration after a full meal
  • Monitoring of liver function during continuous treatment
  • Caution in cases of hepatitis and jaundice

Therapeutic Class

  • Drugs for subcutaneous and mycoses

Storage Conditions

  • Store below 25°C
  • Keep in a cool & dry place
  • Keep away from light
  • Keep out of reach of children

Common Questions

  • Duration of effect
  • Onset of action
  • Pregnancy warnings
  • Habit forming properties
  • Breastfeeding warnings
  • General usage tips

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