Legaba 50 mg (Capsule)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Apex pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
Dosage
- Maximum recommended dose for neuropathic pain associated with diabetic peripheral neuropathy is 100 mg three times a day
- Dosing should begin at 50 mg three times a day and may be increased to 300 mg/day
- Recommended dose for postherpetic neuralgia is 75 to 150 mg two times a day
- Recommended dose for fibromyalgia is 300 to 450 mg/day
- Recommended dose range for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day
Administration
- Taken in oral route
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
Drug-Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side-Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Thinking abnormal
- Increased weight
- Increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies with pregabalin in pregnant women
- Small amounts of pregabalin have been detected in the milk of lactating women
- Breastfeeding is not recommended during treatment with pregabalin
Precautions & Warnings
- Angioedema can occur and may be associated with life-threatening respiratory compromise
- Legaba should be discontinued immediately in cases of hypersensitivity reactions
- Antiepileptic drugs increase the risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants
- May cause dizziness and somnolence and impair ability to drive or operate machinery
- Increased seizure frequency may occur if discontinued rapidly
Use in Special Populations
- Safety and effectiveness in pediatric patients not established for certain conditions
Overdose Effects
- Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block
- No specific antidote
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure: Image available
Common Questions about Legaba 50 mg Capsule
- First-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
- Duration of use dependent on improvement in health conditions
- Frequency of use as prescribed by the doctor
- Should be taken after food in prescribed dosage
- Storage and disposal instructions provided
- Works differently for different diseases
- Consultation required before discontinuation
- Compatibility with Diazepam
- May cause weight gain
- Additional quick tips for usage