Tanpot 25 mg (Tablet)
Unit Price: ৳ 4.00 (5 x 10: ৳ 200.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Losartan potassium |
| Company | Albion laboratories limited |
| Also available as |
Indications
- Treatment of hypertension
- Renal protection in type-2 diabetic patients with proteinuria
Pharmacology
- Non-peptide orally active angiotensin II receptor blocker
- Binds to AT1 receptor in various tissues
- Reduces vasoconstriction and aldosterone release
Dosage & Administration
- Usual starting and maintenance dose of 50 mg once daily
- Alternative dose of 25 mg twice daily
- Lower starting dose of 25 mg once daily for patients over 75 years
Interaction
- Reduction of active metabolite levels by rifampicin and fluconazole
- Potentiation of antihypertensive effects with hydrochlorothiazide
- Increases in serum potassium with potassium-sparing diuretics, supplements or salt substitutes
- Attenuation of antihypertensive effect by indomethacin
- Increased risk of renal impairment with multiple drug use
Contraindications
- Pregnant women
- Hypersensitivity to any component of the product
- Concomitant use with Aliskiren in diabetic patients
Side Effects
- Mild and transient side effects
- Common side effects include dizziness, diarrhea, nasal congestion, cough, and upper respiratory infection
- Other potential side effects include fatigue, edema, abdominal pain, chest pain, nausea, headache, and pharyngitis
Pregnancy & Lactation
Category D for pregnancy, potential excretion in human milk
Precautions & Warnings
- Reduced fetal renal function and increased fetal and neonatal morbidity and death in second and third trimesters of pregnancy
- Risk of symptomatic hypotension in intravascularly volume-depleted patients
- Significantly increased plasma concentration in cirrhotic patients
- Changes in renal function including renal failure reported in renal impaired patients
Use in Special Populations
- No initial dosage adjustment for mild renal impairment
- Lower starting dose for moderate to severe renal impairment or dialysis patients
- Lower dose for patients with a history of hepatic impairment
Therapeutic Class
Angiotensin II receptor blocker
Storage Conditions
Store in a dry place away from light and heat, keep out of the reach of children