Ceftobac 500 mg/vial (IM Injection)
500 mg vial: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Novatek pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Bactericidal activity against Gram-positive and Gram-negative organisms
- Interferes with bacterial cell wall synthesis
- High stability in the presence of beta lactamases
- Long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Excretion in urine and bile/feces
- Highly protein bound (95%)
Dosage
- Adult dosage: 1 to 2 gm by intravenous or intramuscular administration once a day or equally divided doses twice a day
- Maximum adult dose: 4 gm/day
- Infants and Children dosage: 50 to 75 mg/kg intravenous or intramuscular administration once a day or equally divided doses twice a day
- Maximum pediatric dose: 2 gm/day
- Continue therapy for more than 2 days after signs and symptoms have disappeared
- Usual duration of therapy: 4 to 14 days
Administration
- Preparation of Solutions for Intramuscular/Intravenous Injections
- Intramuscular Injection: Dissolve in Lidocaine HCI 1% injection
- Intravenous Injection: Dissolve in Water for injection USP
- Recommended administration over 2-4 minutes for intramuscular or intravenous injection or by tubing infusion over 30 minutes
- Freshly reconstituted solution is recommended
Interaction
- No reported drug interactions
Contraindications
- History of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Not established for safety in human pregnancy
- Excretion in human milk
- Caution during lactation
Precautions & Warnings
- Risk of anaphylactic shock
- Possible gallbladder sludge revelation
- Blood picture monitoring during prolonged treatment
Use in Special Populations
- Avoid use in premature and newborn neonates (up to 28 days of age)
Overdose Effects
- No specific antidote
- Symptomatic treatment for overdosage
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place below 30°C
- Keep away from light & moisture
- Keep out of the reach of children