Ceftobac 1 gm/vial (IV Injection)

1 gm vial: ৳ 160.00

Medicine Details

Title and Categories

  • Ceftobac Injection
  • Pharmaceutical Products
  • Parenteral Antibiotics
  • Cephalosporin Antibiotics

Major Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibiotic
  • Bactericidal activity
  • Potent against Gram-positive and Gram-negative organisms
  • Interferes with bacterial cell wall synthesis
  • Stable in the presence of beta lactamases
  • Long plasma elimination half-life of 6 to 9 hours

Dosage

  • Adult dose: 1 to 2 gm IV or IM once a day
  • Usual duration of therapy: 4 to 14 days
  • Infant and Children dose: 50 to 75 mg/kg IV or IM once a day
  • Maximum dose for adults: 4 gm/day
  • Maximum dose for children: 2 gm/day

Administration

  • Preparation for Intramuscular Injection
  • Preparation for Intravenous Injection
  • Recommended infusion period of 30 minutes
  • Administration over 2-4 minutes

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects: diarrhea, nausea, vomiting
  • Cutaneous reactions: rash, pruritus, urticaria
  • Hematologic reactions: eosinophilia, thrombocytopenia
  • Hepatic reactions: elevations of SGOT or SGPT
  • CNS reactions: nervousness, confusion, headache
  • Rare occurrence of local phlebitis following IV administration

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Excretion in human milk

Precautions & Warnings

  • Risk of anaphylactic shock
  • Possibility of gallbladder sludge
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

  • Not to be given to premature and newborn neonates

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Keep away from light and moisture

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