Repopain 30 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 55.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Novatek pharmaceuticals ltd
Also available as
Repopain 10 mg tablet

Indications

  • Short-term management of post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decreasing eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
  • Inhibits synthesis of prostaglandins
  • Biological activity associated with S-form
  • Highly protein bound
  • Metabolized in liver
  • Excreted in urine

Pharmacology

  • Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
  • Inhibits cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Tablet recommended dose: 10 mg every 4-6 hours
  • Injection recommended dose: varies by age and condition
  • Maximum daily dose should not exceed specified limits

Interaction

  • Increase in side effects with other NSAIDs or aspirin
  • Enhanced anti-coagulant effect with anti-coagulants
  • Reduction in anti-hypertensive effect with beta blockers
  • Increased risk of renal impairment with ACE inhibitors
  • Enhanced toxicity of methotrexate

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Children under 16 years of age
  • Prophylactic analgesic use before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melena
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

  • FDA Pregnancy category: C
  • Avoid use in pregnancy and lactation unless benefits outweigh risks to fetus

Precautions & Warnings

  • Caution in patients over 65 years
  • Caution in patients with active or suspected peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
  • Discontinue use if corneal epithelial breakdown is observed

Therapeutic Class

  • Rheumatoid Arthritis drugs
  • Non-Opioid Analgesics

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of reach of children

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