Rabipep 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 5.75 (5 x 10: ৳ 287.50)
Strip Price: ৳ 57.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Rabeprazole sodium |
| Company | Novatek pharmaceuticals ltd |
Indications
- Treatment of active duodenal ulcer
- Treatment of active benign gastric ulcer
- Symptomatic treatment of erosive or ulcerative gastro-esophageal reflux disease (GERD)
- Long-term management of gastro-esophageal reflux disease (GERD)
- Symptomatic treatment of moderate to very severe gastro-esophageal reflux disease (symptomatic GERD)
- Treatment of Zollinger-Ellison Syndrome
- Eradication of Helicobacter pylori in patients with peptic ulcer disease
Pharmacology
- Suppression of gastric acid secretion
- Inhibition of gastric H+/K+-ATPase
- Characterized as a gastric proton-pump inhibitor
Dosage
- Recommended oral doses for different conditions
- Variations in dosage based on patient response and specific conditions
- Dosage for pediatric patients
- Treatment duration for different indications
Administration
- Recommended time for taking tablets
- Instructions for consumption before eating
- Caution against chewing or crushing tablets
Interaction
- Potential interaction with pH-dependent compounds
- Possible decrease in plasma levels when co-administered with ketoconazole or itraconazole
- No interaction with liquid antacids observed
- Absorption of atazanavir is pH-dependent, hence co-administration is not recommended
Contraindications
- Hypersensitivity to the active substance or excipients
- Contraindicated in pregnancy and during breastfeeding
Side Effects
- Common side effects reported
- Well-tolerated in both short-term and long-term studies
Pregnancy & Lactation
- US FDA pregnancy category 'C'
- No adequate and well-controlled studies in pregnant women
- Likely excretion in human milk
- Consideration of risks and benefits for nursing mothers
Precautions & Warnings
- Importance of excluding malignancy prior to treatment
- Regular surveillance for long-term treatment
- Possible increase in risk of fractures with long-term use
- Caution in patients at risk of osteoporosis
- Potential cross-hypersensitivity reactions
- Warning against chewing or crushing tablets
- Reports of blood dyscrasias and hepatic enzyme abnormalities
- Caution in patients with hepatic impairment
- Not recommended for co-administration with atazanavir
- Possible increased risk of gastrointestinal infections
- Risk of hypomagnesaemia
- Influence on vitamin B12 absorption
- Association with subacute cutaneous lupus erythematosus (SCLE)
- Potential interference with laboratory tests
Use in Special Populations
- No dosage adjustment for patients with renal or hepatic impairment
- Not recommended for use in children
Overdose Effects
- Maximum established exposure
- Minimal and reversible effects
- No specific antidote known
- Treatment should be symptomatic and supportive
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Temperature and environmental requirements
- Protection from light and moisture
- Keep out of the reach of children
Chemical Structure
- Molecular formula
- Chemical structure image
Common Questions about Rabipep 20 mg Tablet
- Description of the tablet and its function
- Common uses of Rabipep 20 mg Tablet
- List of common side effects
- Instructions for taking the tablet
- Recommendations for pregnant or breastfeeding individuals
- Response to overdose, duration of treatment, and additional precautions
- Advisory tips and precautions
- Effects of long-term use on bone health and calcium deficiency
- Potential use of vitamin D with the tablet