Dofolin 200 mg (Tablet)

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Doxophylline
Company Euro pharma ltd
Also available as

Indications

  • Bronchial asthma
  • Bronchospasm
  • Chronic obstructive pulmonary disease (COPD)
  • Pulmonary disease with spastic bronchial component

Pharmacology

  • Novel bronchodilator
  • Selective inhibition of phosphodiesterase 4
  • Relaxes bronchial smooth muscle
  • Inhibition of platelet activating factor (PAF)
  • Inhibition of leukotriene production

Dosage & Administration

  • Dosage for Elderly: 200 mg tablet two or three times daily
  • Dosage for Adults: 400 mg tablet two or three times daily
  • Dosage for Children (12 years and above): 10 ml syrup or 200 mg tablet two or three times daily
  • Dosage for Children (6-12 years): 6-9 mg/kg body weight two times daily
  • Instructions for Doxophylline SR tablet usage

Interaction

  • Avoid concurrent use with other xanthine preparations
  • Limit consumption of beverages and food containing caffeine
  • Exercise caution when administered together with ephedrine or sympathomimetic drugs
  • Potential impact of concurrent administration with erythromycin, TAO, lincomycin, clindamycin, allopurinol, cimetidine, influenza vaccine, propanolol, phenytoin, and other anticonvulsants
  • Increased clearance with cigarette smoking
  • Possible need to increase drug dosage in certain cases

Contraindications

  • Known hypersensitivity to the drug or other xanthine derivatives
  • Acute myocardial infarction
  • Hypotension
  • Lactation

Side Effects

  • Nausea
  • Vomiting
  • Epigastric pain
  • Headache
  • Irritability
  • Insomnia
  • Tachycardia
  • Extrasystoles
  • Tachypnea
  • Hyperglycemia
  • Albuminuria
  • Severe cardiac arrhythmias
  • Tonic-clonic seizure

Pregnancy & Lactation

  • Animal test results
  • Evaluation during pregnancy on a case-by-case basis
  • Contraindicated during lactation
  • Effects on ability to drive and use machines

Precautions & Warnings

  • Factors affecting hepatic clearance
  • Monitoring blood levels in certain cases
  • Caution in patients with cardiac disease, hypertension, hypoxemia, hyperthyroidism, liver disease, peptic ulcer, renal impairment
  • Special caution in patients with congestive heart failure
  • No risk of addiction or dependence

Overdose Effects

  • Cardiac arrhythmias
  • Tonic-clonic seizure
  • Discontinuation of treatment in case of side effects
  • Symptomatic treatment of cardiovascular collapse

Therapeutic Class

  • Bronchodilator
  • Methyl xanthine derivatives

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children
  • Usage only on prescription of specialist physician

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