Sitaglap M 50 mg+500 mg (Tablet)
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin metformin hydrochloride |
| Company | Euro pharma ltd |
| Also available as |
Title and Description
- Combination Oral Hypoglycemic Tablet for Type 2 Diabetes Mellitus
Categories
- Medicine
- Pharmacology
- Diabetes Management
- Diabetes Medication
Color Options
- White
Dosage Form
- Film-coated tablet
- Extended-release tablet
Usage Frequency
- Twice daily
Usability Features
- Individualized dosage
- Gradual dose escalation
- Administration with meals
- Maximum recommended daily dose
- Co-administration with other medications
Technical Specifications
- 100 mg sitagliptin
- 2000 mg metformin
- Sitagliptin phosphate monohydrate INN
- Metformin hydrochloride BP
- Renal function monitoring
- Annual assessment of renal function
- Vitamin B12 level monitoring
- Hematologic parameter measurement
Material
- Antihyperglycemic agents
- Sitagliptin
- Metformin HCl
- Biguanide class
Design Elements
- Film coating
- Combination therapy
- Cationic drug interactions
- Renal tubular secretion
Mode of Action
- Dipeptidyl peptidase-4 (DPP-4) inhibitor
- Inhibition of incretin hormones inactivation
- Insulin synthesis and release stimulation
- Glucagon secretion reduction
- Hepatic glucose production decrease
- Intestinal glucose absorption decrease
- Peripheral glucose uptake and utilization increase
Dimensions
- Standard tablet size
Function
- Improvement of glycemic control
- Adjunct to diet and exercise
- Gastrointestinal side effects reduction
Interaction
- Cationic drugs caution
- Phenprocoumon interaction
- Levothyroxine interaction
Contraindications
- Renal disease or dysfunction
- Metabolic acidosis
- Hypersensitivity reaction
- Radiologic studies involving contrast materials
Side Effects
- Diarrhea
- Upper respiratory tract infection
- Headache
- Hypoglycemia
- Nasopharyngitis
- Nausea/vomiting
- Flatulence
- Abdominal discomfort
- Indigestion
- Asthenia
Pregnancy & Lactation
- Pregnancy Category B
- Caution during nursing
Precautions & Warnings
- Lactic acidosis risk
- Thyroid-stimulating hormone (TSH) monitoring
- Vitamin B12 level monitoring
- Hepatic disease caution
- Renal function assessment
- Acute pancreatitis risk
- Excessive alcohol intake warning
- Insulin use during stress or decreased intake period
- Allergic and hypersensitivity reactions monitoring
- Macrovascular risk reduction absence
Overdose Effects
- Supportive measures for overdose
- Dialyzability of sitagliptin
- Metformin dialyzability and clearance rate
- Pancreatitis risk in metformin overdose
Therapeutic Class
- Oral hypoglycemic preparations
Storage Conditions
- Store below 25°C
- Dry place away from light
- Keep out of reach of children
- Do not use after expiry date
- Dispense only on physician's prescription