Esoflux 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Centeon pharma ltd
Also available as
Esoflux 40 mg capsule

Title

  • Esoflux 20 mg Capsule

Categories

  • Medicine
  • Gastroenterology
  • Pharmacology
  • Esomeprazole

Description

  • Proton pump inhibitor for relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Healing of Duodenal & Gastric ulcers
  • Oral and IV administration
  • Drug interactions and contraindications
  • Side effects and precautions
  • Pregnancy and lactation considerations
  • Special populations and storage conditions

Dosage Form

  • Tablet
  • Capsule
  • Oral Suspension
  • IV Injection

Dosage Instructions

  • 20 mg or 40 mg Once Daily for 4-8 Weeks for healing of erosive esophagitis
  • 20 mg Once Daily for maintenance of healing of erosive esophagitis
  • 20 mg Once Daily for symptomatic GERD
  • Triple Therapy for Helicobacter pylori eradication
  • 20-80 mg dose for Zollinger-Ellison Syndrome
  • 20-40 mg dose for acid-related Dyspepsia
  • 20 mg dose for Duodenal ulcer and 20-40 mg dose for Gastric ulcer

Administration Instructions

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • IV injection to be administered over a period of at least 3 minutes

Interaction Information

  • Extensive metabolism by CYP2C19 and CYP3A4
  • No clinically relevant interactions with specific CYP enzymes expected
  • Potential interference with CYP2C19
  • Inhibition of gastric acid secretion affecting drug absorption
  • No significant interactions with specific drugs observed

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy and Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions and Warnings

  • Symptomatic response to therapy does not rule out gastric malignancy
  • Instructions for patients with difficulty swallowing capsules
  • Use of antacids while taking Esoflux
  • Safety and effectiveness not established in paediatric patients

Special Populations

  • No observed differences in safety and efficacy between elderly and younger individuals
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • Renal impairment not expected to alter pharmacokinetics

Overdose Effects

  • Lethal dose in rats observed at 510 mg/kg
  • Signs of acute toxicity include reduced motor activity and tremors
  • No specific antidote known, symptomatic and supportive treatment advised

Storage Conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg

Commonly Asked Questions

  • What is Esoflux 20 mg Capsule?: A proton pump inhibitor used to reduce stomach acid production and treat various conditions.
  • What is Esoflux 20 mg Capsule used for?: Relief from heartburn, healing of erosive esophagitis, prevention of recurrence, and more.
  • What are the side effects of Esoflux 20 mg Capsule?: Common side effects include headaches, diarrhea, nausea, and others.
  • Can I take Esoflux 20 mg Capsule if I am pregnant or breastfeeding?: Consult a doctor for risks and benefits if essential.
  • How long does it take for Esoflux 20 mg Capsule to work?: Usually starts working within a few hours of intake.
  • Quick Tips:
    • Esoflux is well-tolerated and provides long-term relief
    • Avoid eating late at night or before bedtime
    • Consult a doctor for specific symptom concerns

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