Avastrol 20 mg (Tablet)

Unit Price: ৳ 18.00 (2 x 10: ৳ 360.00)
Strip Price: ৳ 180.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Centeon pharma ltd
Also available as
Avastrol 10 mg tablet

Product Title

  • Avastrol 20 mg Tablet

Categories

  • Cholesterol-lowering medication
  • Hyperlipidemia treatment
  • Cardiovascular health

Description

Avastrol 20 mg Tablet is a selective inhibitor of HMG-CoA reductase used for reducing total cholesterol, LDL cholesterol, apolipoprotein B, and triglycerides levels in various diseases when response to diet and other non-pharmacological measures is inadequate.

Dimensions

  • N/A

Color Options

  • N/A

Functions

  • Reduces elevated total cholesterol
  • Lowers LDL cholesterol levels
  • Lowers apolipoprotein B levels
  • Reduces triglycerides levels
  • Prevents cardiovascular events
  • Adjunct to diet for hypercholesterolemia
  • Treatment for dyslipidemia

Materials

  • Atorvastatin calcium

Technical Specifications

  • Selective inhibitor of HMG-CoA reductase
  • Rapid absorption after oral administration
  • Maximum plasma concentrations within 1 to 2 hours
  • Approximately 14% absolute bioavailability
  • Approximately 30% systemic availability of HMG-CoA reductase inhibitory activity
  • Approximately 381 liters mean volume of distribution
  • 98% bound to plasma proteins
  • 70% of circulating inhibitory activity attributed to active metabolites
  • Ortho- and parahydroxylated metabolites equivalents to Atorvastatin in vitro inhibition
  • Metabolized by cytochrome P450 3A4
  • Approximately 14 hours plasma elimination half-life
  • Less than 2% recovered in urine after oral administration

Design Elements

  • Tablet form

Usability Features

  • Effective as an adjunct to diet
  • Can be taken with or without food
  • Dosing can be adjusted based on response
  • Reduces elevated serum triglyceride levels
  • Increases hepatic LDL receptors for enhanced uptake and catabolism of LDL

Indications

  • Reduction of total cholesterol and LDL cholesterol in familial hypercholesterolemia
  • Treatment of mixed dyslipidemia
  • Reduction of cholesterol in hypertriglyceridemia
  • Treatment of dysbetalipoproteinaemia
  • Reduction of cardiac ischemic events in coronary artery disease
  • Reduction of cholesterol concentrations in hypercholesterolemia linked to diabetes mellitus or renal transplantation

Dosage & Administration

  • For adults: Usually 10 mg once daily; maximum 80 mg once daily if necessary
  • For children (10-18 years): Initially 10 mg once daily, increased to max. 20 mg once daily if necessary
  • Initial doses for familial hypercholesterolemia and prevention of cardiovascular events

Interactions

  • Increased risk of myopathy with concurrent administration of certain drugs
  • Altered plasma concentrations when coadministered with antacid, colestipol, digoxin, erythromycin, oral contraceptives
  • No clinically significant effect on prothrombin time when administered to patients receiving chronic warfarin treatment

Contraindications

  • Hypersensitivity to any component of the medication
  • Active liver disease or unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Not to be used by breastfeeding women

Precautions & Warnings

  • Liver function tests should be performed before the initiation of treatment and periodically thereafter
  • Used with caution in patients who consume substantial quantities of alcohol or have a history of liver disease
  • Therapy should be discontinued if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

Use in Special Populations

  • Plasma concentrations are higher in healthy elderly subjects than in young adults
  • No clinically significant difference in LDL-C reduction between men and women

Overdose Effects

  • Specific treatment not available
  • Supportive measures should be instituted
  • Liver function tests should be performed and serum CK levels should be monitored

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C33H35FN2O5
  • Chemical Structure Image: URL to chemical structure image

Common Questions

  • What is Avastrol 20 mg Tablet?
  • How should I take Avastrol 20 mg Tablet?
  • What are the uses of Avastrol 20 mg Tablet?
  • What are the Side Effects of Avastrol 20 mg Tablet?
  • What are the instructions for storage and disposal of Avastrol 20 mg Tablet?
  • Is Avastrol 20 mg Tablet used for lowering cholesterol?
  • Will taking Avastrol 20 mg Tablet increase my risk of diabetes?
  • For how long do I need to take Avastrol 20 mg Tablet? Is it safe for long-term use?
  • Does Avastrol 20 mg Tablet cause weight loss?
  • Can I stop taking Avastrol 20 mg Tablet?
  • Does Avastrol 20 mg Tablet cause memory loss?
  • Does Avastrol 20 mg Tablet make you tired?
  • Can Avastrol 20 mg Tablet be prescribed to children?
  • Is Avastrol 20 mg Tablet a blood thinner?
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