Fludex 150 mg (Capsule)
Unit Price: ৳ 21.00 (1 x 10: ৳ 210.00)
Strip Price: ৳ 210.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Medicon pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Triazole antifungal agent, inhibitor of fungal cytochrome P-450 dependent enzymes
Dosage & Administration
- Adults:
- Specific dosages for various indications
- Dosage modifications based on age and renal impairment
- Child over 1 year:
- Dosages for different indications
- Dosage based on weight
- Elderly patient: Normal dose usage if no evidence of renal impairment
- Renal Impairment: No adjustment in single dose therapy, dosage modification in multiple dose therapy based on creatinine clearance and dialysis
Interaction
- Effect on prothrombin time after warfarin administration
- Prolongation of serum half-life of concomitantly administed oral sulphonyl ureas
- Increase in plasma concentrations of fuconazole by hydrochlorothiazide
- Increase in phenytoin levels
- Effect on combined oral contraceptive, cyclosporin, theophyline, and other medications
Contraindications
Hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rash
- Anaphylaxis
Pregnancy & Lactation
Adverse fetal effects seen in animals at dose levels associated with maternal toxicity
Precautions & Warnings
- Abnormalities of hepatic, renal, haematological and other biochemical function tests in some patients
- Rare occurrences of hepatic necrosis
- Exfoliative cutaneous reactions
- Risk-benefit ratio assessment in patients with significant rise of liver enzymes
- Use during lactation not recommended
- Unlikely to impair ability to drive or use machinery
Use in Special Populations
- Use in the elderly
- Dosage adjustments based on renal impairment
Overdose Effects
- Supportive measures and symptomatic treatment
- Gastric lavage if necessary
- Forced volume diuresis to increase elimination rate
- Haemodialysis to decrease plasma levels
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Keep in a dry place away from light and heat, keep out of the reach of children