Jaktor XR 11 mg (Tablet (Extended Release))
Unit Price: ৳ 75.00 (3 x 10: ৳ 2,250.00)
Strip Price: ৳ 750.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tofacitinib |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Rheumatoid Arthritis treatment for adults
- Psoriatic Arthritis treatment for adults
- Ulcerative Colitis treatment for adults
Pharmacology
- Autoimmune disease characterized by dysregulation of pro-inflammatory cytokines
- Janus Kinase (JAK) inhibition
- Prevention of body's response to cytokine signals
Dosage & Administration
- Recommended dosage for Rheumatoid Arthritis: Tofacitinib 5 mg twice daily or 11 mg once daily
- Recommended dosage for Psoriatic Arthritis: Tofacitinib 5 mg twice daily or 11 mg once daily
- Recommended dosage for Ulcerative Colitis: Tofacitinib 10 mg twice daily for at least 8 weeks
Interaction
- Interaction with potent inhibitors of Cytochrome P450 3A4 (CYP3A4)
- Interactions with moderate inhibition of CYP3A4 and potent inhibition of CYP2C19
- Interactions with potent CYP inducers (e.g. Rifampin)
Side Effects
- Commonly reported adverse reactions
Pregnancy & Lactation
- Pregnancy Category C
- Potentially excreted in human milk
Precautions & Warnings
- Avoid use during active serious infection
- Caution in patients at risk of gastrointestinal perforations
- Recommended laboratory monitoring
- Avoid use with live vaccines
- Do not initiate if certain blood cell counts are low
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- Caution in treating elderly patients
- Dosage adjustment for patients with renal or hepatic impairment
Therapeutic Class
- Immunosuppressant
Storage Conditions
- Store below 30°C
- Protect from light and moisture