Jaktor XR 11 mg (Tablet (Extended Release))

Unit Price: ৳ 75.00 (3 x 10: ৳ 2,250.00)
Strip Price: ৳ 750.00

Medicine Details

Category Details
Generic Tofacitinib
Company Beacon pharmaceuticals plc
Also available as
Jaktor 5 mg tablet Tofacinix 11 mg tablet

Indications

  • Rheumatoid Arthritis treatment for adults
  • Psoriatic Arthritis treatment for adults
  • Ulcerative Colitis treatment for adults

Pharmacology

  • Autoimmune disease characterized by dysregulation of pro-inflammatory cytokines
  • Janus Kinase (JAK) inhibition
  • Prevention of body's response to cytokine signals

Dosage & Administration

  • Recommended dosage for Rheumatoid Arthritis: Tofacitinib 5 mg twice daily or 11 mg once daily
  • Recommended dosage for Psoriatic Arthritis: Tofacitinib 5 mg twice daily or 11 mg once daily
  • Recommended dosage for Ulcerative Colitis: Tofacitinib 10 mg twice daily for at least 8 weeks

Interaction

  • Interaction with potent inhibitors of Cytochrome P450 3A4 (CYP3A4)
  • Interactions with moderate inhibition of CYP3A4 and potent inhibition of CYP2C19
  • Interactions with potent CYP inducers (e.g. Rifampin)

Side Effects

  • Commonly reported adverse reactions

Pregnancy & Lactation

  • Pregnancy Category C
  • Potentially excreted in human milk

Precautions & Warnings

  • Avoid use during active serious infection
  • Caution in patients at risk of gastrointestinal perforations
  • Recommended laboratory monitoring
  • Avoid use with live vaccines
  • Do not initiate if certain blood cell counts are low

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • Caution in treating elderly patients
  • Dosage adjustment for patients with renal or hepatic impairment

Therapeutic Class

  • Immunosuppressant

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture

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