Olapar 150 mg (Tablet)
Unit Price: ৳ 1,700.00 (1 x 28: ৳ 47,600.00)
Strip Price: ৳ 47,600.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Olaparib |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Breast Cancer
- Ovarian Cancer
- Germline BRCA mutation
- Metastatic setting
- Platinum sensitive relapsed
- Hormone receptor-positive breast cancer
- Neoadjuvant setting
- Adjuvant setting
Pharmacology
- Inhibitor of PARP enzymes
- DNA transcription
- Cell cycle regulation
- Tumor cell line inhibition
- Tumor growth inhibition
- Cell death induction
- Absorption characteristics
- Distribution characteristics
- Metabolism characteristics
- Excretion characteristics
Dosage & Administration
- Recommended dosage
- Dose modifications for adverse reactions
- Dose modifications for use with CYP3A inhibitors
- Dose modifications for patients with renal impairment
- Pediatric use
Interaction
- Anticancer agents interaction
- Drugs that may increase Olapar plasma concentrations
- Drugs that may decrease Olapar plasma concentrations
Contraindications
- Hypersensitivity to the drug or its ingredients
Side Effects
- Anemia
- Dermatitis allergic
- Neutrophil count decreased
- Platelet count decreased
- Discontinuation due to adverse events
Pregnancy & Lactation
- Fetal harm potential
- Embryo-fetal toxicity
- Excretion in human milk
- Adverse reactions in nursing infants
Precautions & Warnings
- Myelodysplastic Syndrome/Acute Myeloid Leukemia risk
- Pneumonitis risk
Overdose Effects
- General supportive measures
Therapeutic Class
- Targeted Cancer Therapy
Storage Conditions
- Storage temperature
- Protection from light
- Keep out of the reach of children