Lipofit 10% (IV Infusion)

Indications

• Source of calories and essential fatty acids for parenteral nutrition
• Treatment for preoperative and postoperative nutritional disturbances
• Management of nutritional disorders or disturbances of nitrogen balance
• Reducing nitrogen losses in burns patients
• Usage in cases of prolonged unconsciousness
• Support for impaired renal function
• Treatment for cachexia and essential fatty acid deficiency

Composition

• Refined Soyabean Oil BP 10 gm
• Purified Egg Lecithin Ph. Gr. 1.2 gm
• Glycerol BP 2.25 gm

Pharmacology

• Prevents Essential Fatty Acid Deficiency (EFAD)
• Provides a mixture of neutral triglycerides, predominantly unsaturated fatty acids
• Formulated as a concentrated source of energy
• Isotonic and may be given by central or peripheral venous route

Dosage

• Part of Total Parenteral Nutrition (TPN) with specific administration rates for adults, children, and infants
• Dosage for correcting EFAD
• Recommendation to discard leftover contents of opened bottles

Administration

• Can be given via a peripheral or central vein
• Can be administered simultaneously with amino acids and/or glucose

Interaction

• Potential interaction with insulin and heparin

Contraindications

• Contraindicated in severely disordered fat metabolism
• Hypersensitivity to egg, soya, or peanut protein

Side Effects

• Possible side effects include rise in body temperature, shivering, chills, nausea/vomiting
• Rare reports of hypersensitivity reactions, thrombosis, haemolysis, circulatory effects

Pregnancy & Lactation

• Caution advised during pregnancy and lactation due to unestablished safety

Precautions & Warnings

• Contain soya oil and egg lecithin, potential for allergic reactions
• Cross-allergic reactions observed between soya-bean and peanut
• Requires caution in various health conditions and patient groups

Overdose Effects

• Potential for fat overload syndrome with symptoms like bone marrow depression, anaemia, and shock

Therapeutic Class

• Parenteral nutritional preparations

Storage Conditions

• Store at 15°C to 30°C in a dry place protected from light
• Discard leftover contents of opened bags or bottles
• Contain no preservatives

Related Brands

• Omegaven 10% (IV Infusion) - radiant-pharmaceuticals-ltd