Anitid 75 mg/5 ml (Syrup)
100 ml bottle: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Team pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
Mode of Action
- Competitively blocks histamine at H2-receptors of the gastric parietal cells
- Inhibits gastric acid secretion
- Does not affect pepsin secretion
- Does not affect serum gastrin
Dosage & Administration
- Usual dosage is 150 mg twice daily or 300 mg as a single daily dose
- Dosage for reflux oesophagitis is 150 mg twice daily or 300 mg at bedtime
- Dosage for Zollinger Ellison syndrome is 150 mg 3 times daily
- Dosage for episodic dyspepsia is 150 mg twice daily or 300 mg at bedtime
- Child dosage is 2-4 mg/kg twice daily
- Dosage for IV injection and IV infusion varies
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- No evidence of harm to the fetus
- Caution needed during pregnancy and lactation
Precautions & Warnings
- Use with caution in patients with impaired renal and hepatic function
Use in Special Populations
- Similar ulcer healing rates in elderly patients
- No significant difference in adverse effects in elderly patients
Overdose Effects
- No particular problems expected following overdosage
- Symptomatic and supportive therapy recommended
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Specific instructions for slow IV injection
- Dilution guidelines for intermittent slow IV infusion
- Dilution recommendations for continuous IV infusion
- Special dilution instructions for patients with hypersecretory conditions
Storage Conditions
- Store in a cool and dry place
- Protect from light