Apidone 10 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Team pharmaceuticals ltd |
| Also available as |
Indications
- Dyspeptic symptom complex
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- Gastroprokinetic action
- Blocks dopamine receptors
- Restores normal gastrointestinal motility
- Enhances gastric emptying
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Usual recommended oral dose for adults and children
- Rectal administration in suppositories
Interaction
- Concomitant administration of anticholinergic drugs
- Antacids and antisecretory drugs
- Main metabolic pathway through CYP3A4
- CYP3A4 inhibitors
- Potentiation and suppression of action with other drugs
Contraindications
- Known hypersensitivity
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions
Pregnancy & Lactation
- Use during the first trimester justified by therapeutic benefit
- No evidence of increase in risk of malformations in humans
- Excretion in breast milk
- Effects on ability to drive and use machines
Precautions & Warnings
- Caution in the case of children
- Increased risk of extra-pyramidal reactions in young children
- Use with caution in patients with hepatic impairment
Use in Special Populations
- Use in infants
- Use in liver disorders
- Use in kidney disorders
Overdose Effects
- Symptoms of overdosage
- Administration of activated charcoal
- Control of extrapyramidal reactions
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure Image
Common Questions about Apidone 10 mg Tablet
- Used for treating nausea and vomiting
- Dosage and duration guidance
- Caution with mental focus
- Avoid alcohol consumption
- Management of side effects
- Consultation for usage longer than 7 days