Temoket 30 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 55.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Team pharmaceuticals ltd |
| Also available as |
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relieves pain, inflammation, and light sensitivity after ocular surgery
- Decreases eye inflammation or redness caused by seasonal allergies
Description
- Belongs to the pyrrolo-pyrrole group of NSAID drugs
- Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Inhibits synthesis of prostaglandins
- Biological activity associated with the S-form
- Highly protein bound and largely metabolized in the liver
Pharmacology
- Potent analgesic of the NSAIDs
- Inhibits the cyclooxygenase enzyme system
- Demonstrates minimal anti-inflammatory effect at its analgesic dose
Dosage & Administration
- Recommended tablet dose: 10 mg every 4-6 hours for short-term use (up to 7 days)
- Injection may be used as single or multiple doses for moderately severe, acute pain
- Different dosing recommendations for patients of different ages and conditions
- Recommended dose for eye drops: 1 drop in each eye 4 times daily
Interaction
- Other NSAIDs or aspirin increase Temoket's side effects
- Anti-coagulants enhance anti-coagulant effect
- Beta Blockers reduce the anti-hypertensive effect
- ACE Inhibitors increase the risk of renal impairment
- Methotrexate enhances the toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Not for use in children under 16 years of age
- Contraindicated as prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melana
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category: C
- Avoid in pregnancy and lactation unless benefits outweigh risks to the fetus
Precautions & Warnings
- Exercised caution in patients over 65 years
- Caution in patients with active/suspected peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue use and monitor patients with evidence of corneal epithelial breakdown
Therapeutic Class
- Rheumatoid Arthritis Drugs
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children