Temtrix 2 gm/vial (IV Injection)

2 gm vial: ৳ 300.00

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity against Gram-positive and Gram-negative organisms
  • Interferes with bacterial cell wall synthesis
  • High degree of stability in the presence of beta lactamases
  • Relatively long plasma elimination half-life
  • Not metabolized in the body
  • Excreted unchanged in urine and bile
  • Highly protein bound (95%)

Dosage

  • Usual dose of 1 to 2 gm for adults
  • Multiple dosage regimens for different infections
  • Maximum daily dose of 4 gm
  • Doses for infants and children based on weight
  • Duration of therapy
  • Specific dosage for uncomplicated gonococcal infections
  • Specific dosage for surgical prophylaxis

Administration

  • Preparation of solutions for intramuscular/intravenous injections
  • Specific instructions for intramuscular and intravenous injection
  • Recommended injection duration and concentration
  • Freshly reconstituted solution recommended
  • Patient tolerance test before treatment

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis after intravenous administration

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution in lactating mothers due to low concentrations in human milk

Precautions & Warnings

  • Anaphylactic shock
  • Shadows suggesting sludge in the gallbladder
  • Blood picture check during prolonged treatment

Use in Special Populations

  • Not to be given to premature and newborn neonates

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Away from light and moisture
  • Keep out of the reach of children

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