Sustogen 250 mg/ml (IM Injection)

Indications

• Testosterone replacement therapy for primary hypogonadal disorders
• Testosterone replacement therapy for secondary hypogonadal disorders
• Treatment after castration
• Treatment of eunuchoidism
• Treatment of hypopituitarism
• Treatment of endocrine impotence
• Treatment of infertility due to spermatogenic disorders
• Treatment of male climacteric symptoms
• Treatment of osteoporosis caused by androgen deficiency
• Masculinization in female-to-male transsexuals

Composition

• Each 1 ml ampoule contains Testosterone propionate 30 mg
• Each 1 ml ampoule contains Testosterone phenylpropionate 60 mg
• Each 1 ml ampoule contains Testosterone isocaproate 60 mg
• Each 1 ml ampoule contains Testosterone decanoate 100 mg in 1 ml arachis oil
• 10 percent benzyl alcohol in the oily solution

Pharmacology

• Principal hormone for growth and development of male sex organs
• Essential for male secondary sex characteristics
• Essential for testes and accessory structures functioning
• Maintenance of libido, sense of well-being, erectile potency
• Prostate and seminal vesicle function

Dosage & Administration

• Adults: Usually one injection of 1 ml every three weeks
• Testosterone administered by deep intramuscular injection
• Children: Safety and efficacy not determined, not recommended for children under 3 years

Interaction

• Enzyme inducing agents may affect testosterone levels
• Adjustment of dose or intervals may be required

Contraindications

• Hypersensitivity to Testosterone or its components
• Known or suspected prostatic carcinoma
• Known or suspected breast carcinoma in males

Side Effects

• Precocious sexual development
• Increased frequency of erections
• Phallic enlargement
• Premature epiphyseal closure
• Priapism
• Oligospermia
• Decreased ejaculatory volume
• Fluid & sodium retention

Pregnancy & Lactation

• Not recommended during pregnancy due to risk of virilization
• Discontinue treatment when pregnancy occurs
• Not recommended during lactation

Precautions & Warnings

• Caution in pre-pubertal boys to avoid premature epiphyseal closure or precocious sexual development
• Regular monitoring of skeletal maturation
• Close medical supervision for patients with cardiac failure, renal dysfunction, hypertension, epilepsy, or migraine
• Caution in men with benign prostatic hyperplasia
• Influence on certain laboratory test results
• Misuse for sports enhancement carries serious health risks

Overdose Effects

• Acute intramuscular toxicity is very low
• Priapism is a symptom of chronic overdose
• Treatment interruption and lower dosage upon priapism occurrence

Therapeutic Class

Male Sex hormones (Androgens)

Storage Conditions

Store in a cool and dry place protected from light (8°C to 30°C)

Related Brands

• Androjet 250 mg/ml (IM Injection) - renata-limited