SB-Met 1000 mg (Tablet)

Unit Price: ৳ 6.00 (30's pack: ৳ 180.00)

Medicine Details

Indications

  • Treatment of type 2 diabetes mellitus
  • Management of diabetes in overweight patients
  • First-line therapy after diet failure

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers basal and postprandial plasma glucose
  • Improves insulin sensitivity
  • Decreases hepatic glucose production

Dosage & Administration

  • Individualized dosage based on effectiveness and tolerance
  • Metformin immediate release tablet
  • Metformin extended release tablet
  • Dosage adjustments for adults and children

Interaction

  • Possible interaction with Furosemide and Nifedipine
  • Potential interaction with cationic drugs
  • Drugs leading to hyperglycemia and loss of glycemic control

Contraindications

  • Hypersensitivity to active substance
  • Acute metabolic acidosis
  • Severe renal failure
  • Acute conditions altering renal function

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Taste disturbance
  • Gastrointestinal disorders
  • Hepatic function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Increased risk of congenital abnormalities

Precautions & Warnings

  • Excretion and accumulation by the kidney
  • Lowering of vitamin B12 level
  • Increased risk of hypoglycemia
  • Regular monitoring of renal function

Use in Special Populations

  • Dosage adjustment for elderly subjects
  • Caution in prescribing to children aged 10-12 years
  • Regular assessment of renal function

Overdose Effects

  • Medical emergency in case of lactic acidosis
  • Treatment with hemodialysis

Therapeutic Class

  • Biguanides

Storage Conditions

  • Store below 30°C
  • Protected from light and moisture
  • Keep out of the reach of children

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