Doperon 5 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 28.19

Medicine Details

Category Details
Generic Domperidone maleate
Company United pharmaceuticals ltd
Also available as

Indications

  • Dyspeptic symptom complex
  • Delayed gastric emptying
  • Gastroesophageal reflux
  • Esophagitis
  • Acute nausea and vomiting
  • Parkinson's disease
  • Radiological studies

Pharmacology

  • Dopamine antagonist
  • ChemoreceptorTrigger Zone (CTZ) blocker
  • Gastroprokinetic action
  • Gastrointestinal motility regulator
  • Gastric emptying facilitator
  • Esophageal peristalsis enhancer

Dosage & Administration

  • Taken before meals
  • Oral dose for adults
  • Oral dose for children
  • Rectal administration for adults
  • Rectal administration for children
  • Maximum daily dose

Interaction

  • Anticholinergic drugs
  • Antacids and antisecretory drugs
  • Metabolic pathway through CYP3A4
  • CYP3A4 inhibitors
  • Influence on the absorption of orally administered drugs
  • Interaction with neuroleptics and dopaminergic agonists

Contraindications

  • Known hypersensitivity
  • Neonates
  • Gastrointestinal hemorrhage
  • Mechanical obstruction
  • Perforation
  • Prolactin releasing pituitary tumor

Side Effects

  • Transient intestinal cramps
  • Extrapyramidal phenomena
  • Increase in plasma prolactin level
  • Neuroendocrinological phenomena
  • Allergic reactions

Pregnancy & Lactation

  • Use during first trimester
  • Excretion in breast milk
  • Concentration in breast milk
  • Effects on newborn
  • Effects on ability to drive and use machines

Precautions & Warnings

  • Caution in children
  • Increased risk of extra-pyramidal reactions
  • Metabolism in liver
  • Caution in hepatic impairment

Use in Special Populations

  • Use in infants
  • Metabolic and blood-brain barrier functions in infants
  • Use in liver disorders
  • Use in kidney disorders
  • Renal insufficiency
  • Dosing frequency adjustment

Overdose Effects

  • Symptoms of overdosage
  • Drowsiness
  • Disorientation
  • Extrapyramidal reactions
  • Activated charcoal as treatment
  • Use of anticholinergic drugs

Therapeutic Class

  • Motility Stimulants
  • Dopamine antagonist
  • Prokinetic drugs

Storage Conditions

  • Temperature
  • Light protection
  • Moisture protection
  • Keep out of children's reach

Chemical Structure

  • Molecular Formula
  • C22H24ClN5O2
  • Chemical Structure Image

Common Questions about Doperon 5 mg/5 ml Suspension

  • Usage of Doperon 5 mg/5 ml Suspension
  • Relief of nausea, vomiting, and indigestion
  • Quick Tips
  • Effects on mental focus
  • Avoidance of alcohol
  • Management of dry mouth
  • Reporting of adverse effects
  • Consultation with doctor for prolonged usage

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