Esigerd 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | United pharmaceuticals ltd |
ProductTitle
- Esigerd 20 mg Tablet
Categories
- Proton Pump Inhibitor
- Gastroesophageal Reflux Disease (GERD) Treatment
- Ulcer Treatment
- Heartburn Relief
Description
- A medication indicated for relief from chronic heartburn
- Used for healing erosive esophagitis and for its maintenance
- Eradicates Helicobacter pylori infection in patients with duodenal ulcer disease
- Effective in treating Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal and gastric ulcers
DosageForm
- Oral capsule
- Oral suspension
- IV injection
- IV infusion
Indications
- Relieves chronic heartburn symptoms
- Heals erosive esophagitis
- Maintains healing of erosive esophagitis
- Eradicates Helicobacter pylori infection
- Treats Zollinger-Ellison Syndrome
- Manages symptoms of acid-related dyspepsia
- Heals duodenal and gastric ulcers
PharmacologyMechanism
- Proton pump inhibitor that suppresses gastric acid secretion
- Inhibits the H+/K+-ATPase in the gastric parietal cell
- Es-isomer providing better acid control
- Absorption occurs at approximately 1.5 hours (Tmax)
- Metabolized in the liver by the CYP enzyme system
AdministrationInstructions
- Swallow whole and take one hour before a meal for tablet or capsule
- Mix contents of the oral suspension with water
- IV injection prepared with 0.9% Sodium Chloride and administrated intravenously over at least 3 minutes
Interaction
- Extensively metabolized in the liver by CYP2C19 and CYP3A4
- Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
- Interferes with the absorption of certain drugs
- No clinically significant interactions with phenytoin, warfarin, quinidine, clarithromycin or amoxicillin
Contraindications
- Contraindicated in patients with known hypersensitivity to any of the formulation
SideEffects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
PregnancyAndLactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects observed in animal studies
- Excretion in milk not studied
- Breastfeeding should be discontinued if essential
PrecautionsAndWarnings
- Symptomatic response to therapy does not exclude the presence of gastric malignancy
- Inform patients about capsule swallowing difficulty
- Applesauce combination for those with swallowing issues
- Use of antacids allowed during treatment
SpecialPopulations
- Safety and effectiveness not established in pediatric patients
- No overall differences observed in safety and efficacy between elderly and younger individuals
- No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
- No alteration of pharmacokinetics expected in renal impairment
OverdoseEffects
- Lethal dose to rats observed at 103 times the human dose on a body surface area basis
- Signs of acute toxicity include reduced motor activity, changes in respiratory frequency, tremor, ataxia, and intermittent clonic convulsions
- No reports of overdose with Esigerd
- No specific antidote known
StorageConditions
- Store at a temperature not exceeding 30°C in a dry place
- Protect from light and moisture
- Keep out of reach of children
ChemicalStructure
C17H19N3O3S
CommonlyAskedQuestions
- What is Esigerd 20 mg Tablet?
- What is Esigerd 20 mg Tablet used for?
- What are the side effects of Esigerd 20 mg Tablet?
- Can I take Esigerd 20 mg Tablet if I am pregnant or breastfeeding?
- How long does it take for Esigerd 20 mg Tablet to work?
QuickTips
- Esigerd 20 mg Tablet provides long-lasting relief
- Avoid late-night eating or eating before bedtime
- Consult your doctor for specific dietary intake of minerals such as calcium and magnesium
- Seek medical attention for signs of kidney problems