Esigerd 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Esomeprazole
Company United pharmaceuticals ltd

ProductTitle

  • Esigerd 20 mg Tablet

Categories

  • Proton Pump Inhibitor
  • Gastroesophageal Reflux Disease (GERD) Treatment
  • Ulcer Treatment
  • Heartburn Relief

Description

  • A medication indicated for relief from chronic heartburn
  • Used for healing erosive esophagitis and for its maintenance
  • Eradicates Helicobacter pylori infection in patients with duodenal ulcer disease
  • Effective in treating Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal and gastric ulcers

DosageForm

  • Oral capsule
  • Oral suspension
  • IV injection
  • IV infusion

Indications

  • Relieves chronic heartburn symptoms
  • Heals erosive esophagitis
  • Maintains healing of erosive esophagitis
  • Eradicates Helicobacter pylori infection
  • Treats Zollinger-Ellison Syndrome
  • Manages symptoms of acid-related dyspepsia
  • Heals duodenal and gastric ulcers

PharmacologyMechanism

  • Proton pump inhibitor that suppresses gastric acid secretion
  • Inhibits the H+/K+-ATPase in the gastric parietal cell
  • Es-isomer providing better acid control
  • Absorption occurs at approximately 1.5 hours (Tmax)
  • Metabolized in the liver by the CYP enzyme system

AdministrationInstructions

  • Swallow whole and take one hour before a meal for tablet or capsule
  • Mix contents of the oral suspension with water
  • IV injection prepared with 0.9% Sodium Chloride and administrated intravenously over at least 3 minutes

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
  • Interferes with the absorption of certain drugs
  • No clinically significant interactions with phenytoin, warfarin, quinidine, clarithromycin or amoxicillin

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

SideEffects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

PregnancyAndLactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

PrecautionsAndWarnings

  • Symptomatic response to therapy does not exclude the presence of gastric malignancy
  • Inform patients about capsule swallowing difficulty
  • Applesauce combination for those with swallowing issues
  • Use of antacids allowed during treatment

SpecialPopulations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences observed in safety and efficacy between elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • No alteration of pharmacokinetics expected in renal impairment

OverdoseEffects

  • Lethal dose to rats observed at 103 times the human dose on a body surface area basis
  • Signs of acute toxicity include reduced motor activity, changes in respiratory frequency, tremor, ataxia, and intermittent clonic convulsions
  • No reports of overdose with Esigerd
  • No specific antidote known

StorageConditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

ChemicalStructure

C17H19N3O3S

CommonlyAskedQuestions

  • What is Esigerd 20 mg Tablet?
  • What is Esigerd 20 mg Tablet used for?
  • What are the side effects of Esigerd 20 mg Tablet?
  • Can I take Esigerd 20 mg Tablet if I am pregnant or breastfeeding?
  • How long does it take for Esigerd 20 mg Tablet to work?

QuickTips

  • Esigerd 20 mg Tablet provides long-lasting relief
  • Avoid late-night eating or eating before bedtime
  • Consult your doctor for specific dietary intake of minerals such as calcium and magnesium
  • Seek medical attention for signs of kidney problems

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