Flucostin 50 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | United pharmaceuticals ltd |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Superficial Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
- Triazole antifungal agent
- Potent inhibitor of fungal cytochrome P-450 dependent enzymes
- Responsible for the synthesis of ergosterol
Dosage & Administration
- Varied dosage for different types of infections
- Dosage adjustments for children, elderly patients, and patients with renal impairment
- Dosage intervals modification based on creatinine clearance
- Oral and IV administration
Interaction
- Interactions with warfarin, sulphonyl ureas, hydrochlorothiazide, phenytoin, rifampicin, oral contraceptives, cyclosporin, food, cemetidine, antacids, theophylline, other medications
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Common side effects: nausea, abdominal discomfort, diarrhea, flatulence
- Rare adverse events: rash, anaphylaxis
Pregnancy & Lactation
- Adverse fetal effects in animals at high dose levels
- Not recommended for use during pregnancy or in women of childbearing potential without adequate contraception
Precautions & Warnings
- Observation of hepatic, renal, hematological, and biochemical function tests
- Assessment of risk-benefit ratio in patients with significant rise of liver enzymes
- Rare development of exfoliative cutaneous reactions
- Discontinue therapy if rash develops
- Not recommended for use during lactation
- Unlikely to impair ability to drive or use machinery
Use in Special Populations
- Normal dose for elderly patients without evidence of renal impairment
- Dosage adjustments for patients with renal impairment
- Dosage intervals and daily dosage modification based on creatinine clearance
Overdose Effects
- Supportive measures and symptomatic treatment
- Forced volume diuresis may increase elimination rate
- Haemodialysis decreases plasma levels
Therapeutic Class
- Drugs for subcutaneous and mycoses
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children