Mefin 500 mg (Tablet)
Unit Price: ৳ 3.01 (10 x 10: ৳ 301.48)
Strip Price: ৳ 30.15
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | United pharmaceuticals ltd |
| Also available as |
Title
- Mefin Tablets
Categories
- Pharmaceuticals
- Diabetes Management
- Oral Antidiabetic Medication
Description
- Mefin Tablets are indicated for the treatment of type 2 diabetes mellitus in adults and children from 10 years of age and adolescents.
DosageAndAdministration
- Dosage must be individualized based on effectiveness and tolerance, usually starting with 500 mg or 850 mg once or twice a day, with meal. Maximum daily dose can be up to 2550 mg per day for adults, and up to 2000 mg per day for children.
ModeOfAction
- Metformin, the active ingredient in Mefin Tablets, lowers both basal and postprandial plasma glucose by decreasing hepatic glucose production, improving insulin sensitivity, and decreasing intestinal absorption of glucose.
Interactions
- Potential interactions with drugs like Furosemide, Nifedipine, Cationic drugs, Cimetidine, thiazides, corticosteroids, sympathomimetics, and others may affect the efficacy of Mefin Tablets.
Contraindications
- Hypersensitivity to the active substance or any excipient, acute metabolic acidosis, severe renal failure, and acute conditions altering renal function or causing tissue hypoxia.
SideEffects
- Possible side effects include gastrointestinal disorders, taste disturbance, lactic acidosis, vitamin B12 absorption decrease, peripheral neuropathy, and skin reactions.
PregnancyAndLactation
- Not recommended during pregnancy, while limited data are available for breastfeeding, so the decision should be made by weighing the benefits against potential risks.
PrecautionsAndWarnings
- Regular monitoring of renal function is advised, risk of hypoglycemia when used in combination with insulin, caution in conditions causing dehydration, serious infections or trauma, and possible interactions with other drugs like anticoagulants.
UseInSpecialPopulations
- Elderly patients may require dosage adjustments based on renal function, while children aged 10-12 years and prepubescent children require particular caution.
OverdoseEffects
- No hypoglycemia seen with doses up to 85 gm, but lactic acidosis may occur, which is a medical emergency and must be treated in a hospital. Hemodialysis is the most effective method for its removal.
TherapeuticClass
- Biguanides
StorageConditions
- Store below 30°C, protected from light and moisture, and keep out of the reach of children.