Oxpro 500 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ciprofloxacin |
| Company | United pharmaceuticals ltd |
| Also available as |
Title
Oxpro Tablet
Categories
- Medicine
- Antibiotic
- Anti-infective
Description
Oxpro is indicated for the treatment of single infection or mixed infections caused by two or more susceptible organisms. It can also be used for infections caused by organisms resistant to other antibiotics including Aminoglycosides, Penicillins and Cephalosporins. Ciprofloxacin is a synthetic quinolone anti-infective agent. Ciprofloxacin has broad spectrum of activity. It is active against most gram negative aerobic bacteria including Enterobacteriaceae and Pseudomonas aeruginosa. Ciprofloxacin is also active against gram-positive aerobic bacteria including penicillinase producing, non penicillinase producing, and methicillin resistant staphylococci, although many strains of streptococci are relatively resistant to the drug.
Dosage
- Dosage range for adults: 100-750 mg twice daily
- Dosage for lower and upper urinary tract infections: 250-500 mg twice daily
- Dosage for respiratory tract infections: 250-500 mg twice daily
- Dosage for gonorrhea: A single dose of 250 or 500 mg
- Cystic fibrosis dosage: 750 mg twice daily
- Dosage adjustment in patients with impaired renal function
- No dosage adjustment necessary for elderly patients
- Dosage for adolescents and children: 7.5-15 mg/kg/day depending on severity of infection
- Duration of treatment: 5 to 10 days for acute infections
- Dosage for extended-release tablet and IV infusion for various infections
Administration
Instruction for the use of Ciprofloxacin IV infusion including checking the bag for leaks, establishing proper fluid level, expelling air from set, and regulating rate of administration.
Interaction
Concurrent administration of Oxpro should be avoided with Magnesium or Aluminum containing antacids or sucralfate or with other products containing Calcium, Iron or Zinc.
Contraindications
Patients with a history of hypersensitivity to Ciprofloxacin or to other quinolones.
Side Effects
- Gastrointestinal disturbances
- Central nervous system disturbances
- Hypersensitivity reactions
- Joint pain
- Mild photosensitivity
- Transient increase in liver enzymes
- Risk of hypoglycemia
- Mental health adverse effects
Pregnancy & Lactation
Use of Ciprofloxacin during pregnancy is not recommended due to potential arthropathy in immature animals. Administration to nursing mothers is not recommended.
Precautions & Warnings
- Use with caution in patients with suspected or known CNS disorders
- Avoid concurrent administration with magnesium/aluminium antacids or sucralfate or with other products containing calcium, iron and zinc
- Avoid concurrent use with milk or yogurt alone
- Consume with or without meals and drink fluids liberally
Use in Special Populations
Oxpro is not a drug of first choice in pediatric population
Overdose Effects
Overdose may lead to seizures, hallucinations, confusion, abdominal discomfort, renal and hepatic impairment
Therapeutic Class
4-Quinolone preparations, Anti-diarrhoeal Antimicrobial drugs
Storage Conditions
Keep below 30°C temperature, protected from light & moisture