Tenkular 5 mg (Tablet)
Unit Price: ৳ 0.40 (20 x 10: ৳ 80.37)
Strip Price: ৳ 4.02
Medicine Details
| Category | Details |
|---|---|
| Generic | Prochlorperazine maleate |
| Company | United pharmaceuticals ltd |
Title
- Tenkular
Categories
- Medicine
- Antiemetic
- Antipsychotic
- Anti vertigo drugs
Description
- Prochlorperazine is a dopamine & histamine antagonist.
- It is used to control severe nausea and vomiting caused by radiation therapy, cancer chemotherapy, surgery, and other conditions.
- It is also used to relieve nausea, vomiting, and attacks of dizziness or spinning sensations (vertigo) associated with Meniere's disease and other inner ear disorders.
- It is used for the treatment of psychotic illness such as schizophrenia (hallucinations and hostility) and acute mania.
- It can be used for the short-term treatment of generalized non-psychotic anxiety.
Mode of Action
- The mechanism of antiemetic activity is due to the blockade of histamine H & dopamine D2 neurotransmitter receptors.
- It also has a weak anticholinergic effect and prevents acid reflux by increasing the tone of the lower esophageal sphincter.
Dosage & Administration
- Children (not recommended in children <10 kg or <2 years): 10-14 kg: 2.5 mg every 12-24 hours as needed; maximum: 7.5 mg/day
- Adults: 5-10 mg 3-4 times/day; usual maximum: 40 mg/day
- Usual dose for nonpsychotic anxiety in adults: 15-20 mg/day in divided doses; do not give doses >20 mg/day or for longer than 12 weeks
Interaction
- Alcohol, barbiturate & other sedatives may increase the CNS depressant action.
- Some drugs like antacids, antiparkinson's drug, lithium may interfere with the absorption of Tenkular.
- Tenkular may interfere with the plasma concentration of propranolol and phenobarbital.
Contraindications
- Hypersensitivity to prochlorperazine or any component of the formulation.
- Severe CNS depression.
- Coma.
- Should not be used in children <2 years of age or <10 kg.
Side Effects
- Drowsiness
- Jaw, neck, and back muscle spasms
- Fine worm-like tongue movements
- Rhythmic face, mouth, or jaw movements
- Skin rash
- Yellowing of the skin or eyes
Pregnancy & Lactation
- No evidence of adverse effects of this drug has been reported during pregnancy & lactation.
Precautions & Warnings
- Caution should be taken while performing tasks that require alertness, such as driving or using machinery.
- The use of alcohol can cause extreme drowsiness.
- This medication may increase sensitivity to sunlight.
- Prolonged sun exposure should be avoided and sunscreen and protective clothing should be taken when anybody is exposed to the sun.
- This medication can reduce sweating making it more susceptible to heatstroke.
Overdose Effects
- Symptoms of overdose include deep sleep, coma, extrapyramidal symptoms, abnormal involuntary muscle movements, and hypotension.
Therapeutic Class
- Anti vertigo drugs
- Anti-emetic drugs
Storage Conditions
- Store below 30°C.
- Protect from light and moisture.
- Keep out of the reach of children.