Esosil 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Silva pharmaceuticals ltd

Indications

  • Chronic heartburn relief
  • Erosive esophagitis healing
  • Maintenance of erosive esophagitis healing
  • Helicobacter pylori eradication
  • Zollinger-Ellison Syndrome treatment
  • Acid-related Dyspepsia relief
  • Duodenal ulcer treatment
  • Gastric ulcer treatment

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Single optical isomer of proton pump inhibitor
  • Enteric-coated pellet formulation
  • Peak plasma levels occur at approximately 1.5 hours
  • High plasma protein binding
  • Extensively metabolized in the liver
  • Metabolized by CYP2C19 and CYP3A4
  • Low urinary excretion

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Dosage varies for different indications
  • Pediatric dosage based on body weight
  • IV infusion duration specified
  • Different dosage for risk reduction of rebleeding
  • Tablet or capsule to be swallowed whole
  • Oral suspension administration instructions

Administration

  • Tablet or capsule to be swallowed whole
  • Oral suspension to be mixed with water before administration
  • IV injection solution preparation and administration
  • IV infusion administration process
  • Specific instructions for administration through a nasogastric or gastric tube

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • Inhibits gastric acid secretion
  • Potential interference with drug absorption
  • Specific drug interactions described

Contraindications

  • Known hypersensitivity to the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied
  • Consideration for breastfeeding

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Specific patient information for administration
  • Use of antacids alongside Esosil
  • Difficulty swallowing capsule workaround

Use in Special Populations

  • Safety and effectiveness in paediatric patients not established
  • No overall differences in safety and efficacy in geriatric use
  • No dosage adjustment for mild to moderate hepatic insufficiency
  • No expected pharmacokinetic alterations in renal insufficiency

Overdose Effects

  • Lethal dose in rat studies
  • Major signs of acute toxicity
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Temperature and moisture considerations
  • Protection from light
  • Keep out of reach of children

Chemical Structure

  • Molecular formula
  • Chemical structure image provided

Common Questions about Esosil 20 mg Capsule

  • Proton pump inhibitor (PPI) description
  • Uses for GERD, ulcers, and too much stomach acid
  • Common side effects
  • Consideration for pregnancy and breastfeeding
  • Onset of action
  • Quick tips for Esosil 20 mg Capsule

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