Esosil 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Silva pharmaceuticals ltd |
Indications
- Chronic heartburn relief
- Erosive esophagitis healing
- Maintenance of erosive esophagitis healing
- Helicobacter pylori eradication
- Zollinger-Ellison Syndrome treatment
- Acid-related Dyspepsia relief
- Duodenal ulcer treatment
- Gastric ulcer treatment
Pharmacology
- Proton pump inhibitor
- Suppresses gastric acid secretion
- Single optical isomer of proton pump inhibitor
- Enteric-coated pellet formulation
- Peak plasma levels occur at approximately 1.5 hours
- High plasma protein binding
- Extensively metabolized in the liver
- Metabolized by CYP2C19 and CYP3A4
- Low urinary excretion
Dosage
- Oral dosage form
- IV Injection or IV infusion
- Dosage varies for different indications
- Pediatric dosage based on body weight
- IV infusion duration specified
- Different dosage for risk reduction of rebleeding
- Tablet or capsule to be swallowed whole
- Oral suspension administration instructions
Administration
- Tablet or capsule to be swallowed whole
- Oral suspension to be mixed with water before administration
- IV injection solution preparation and administration
- IV infusion administration process
- Specific instructions for administration through a nasogastric or gastric tube
Interaction
- Metabolized by CYP2C19 and CYP3A4
- Inhibits gastric acid secretion
- Potential interference with drug absorption
- Specific drug interactions described
Contraindications
- Known hypersensitivity to the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects in animal studies
- Excretion in milk not studied
- Consideration for breastfeeding
Precautions & Warnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Specific patient information for administration
- Use of antacids alongside Esosil
- Difficulty swallowing capsule workaround
Use in Special Populations
- Safety and effectiveness in paediatric patients not established
- No overall differences in safety and efficacy in geriatric use
- No dosage adjustment for mild to moderate hepatic insufficiency
- No expected pharmacokinetic alterations in renal insufficiency
Overdose Effects
- Lethal dose in rat studies
- Major signs of acute toxicity
- No specific antidote known
- Symptomatic and supportive treatment recommended
Storage Conditions
- Temperature and moisture considerations
- Protection from light
- Keep out of reach of children
Chemical Structure
- Molecular formula
- Chemical structure image provided
Common Questions about Esosil 20 mg Capsule
- Proton pump inhibitor (PPI) description
- Uses for GERD, ulcers, and too much stomach acid
- Common side effects
- Consideration for pregnancy and breastfeeding
- Onset of action
- Quick tips for Esosil 20 mg Capsule