Funginil 50 mg (Capsule)
Unit Price: ৳ 8.00 (30's pack: ৳ 240.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Premier pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
- Onychomycosis
- Invasive candidal infections
- Cryptococcal infections
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections
- Fungicidal properties
- Antifungal action
- Antifungal spectrum
- Treatment of coccidioidomycosis
- Treatment of histoplasmosis
Pharmacology
- Triazole antifungal agent
- Cytochrome P-450 inhibitor
- Inhibition of fungal cell membrane synthesis
- Potent antifungal properties
Dosage & Administration
- Adult dosage specifications
- Child dosage specifications
- Dosage adjustments for renal impairment
- Dosage intervals based on creatinine clearance
- Renal clearance considerations in children
Interaction
- Potential interaction with warfarin
- Prolongation of prothrombin time
- Co-administration with sulfonylureas
- Concomitant use with hydrochlorothiazide
- Interactions with phenytoin and rifampicin
- Combined oral contraceptive interactions
- Impact on cyclosporin concentrations
- Absorption interactions with food, cimetidine, and antacids
- Effects on theophylline plasma clearance
Contraindications
- Hypersensitivity to Fluconazole
- Allergic reactions to related triazole compounds
Side Effects
- Gastrointestinal symptoms
- Nausea
- Abdominal discomfort
- Diarrhea
- Flatulence
- Rare occurrence of rash
- Incidence of anaphylaxis
- Tolerability in general population
Pregnancy & Lactation
- Adverse fetal effects in animals
- Avoidance in pregnancy and women of childbearing potential
- Need for adequate contraception
Precautions & Warnings
- Abnormalities of hepatic, renal, and hematological function tests
- Observation of liver enzyme rise
- Possible hepatic necrosis with underlying diseases
- Risk assessment in hepatic abnormalities
- Rare occurrence of exfoliative cutaneous reactions
- Monitoring for severe cutaneous reactions in AIDS patients
- Discontinuation in case of rash development
- Avoidance during lactation
- Effects on driving and machinery use
Use in Special Populations
- Elderly patient dosage considerations
- Dosage adjustments for renal impairment
- Renal clearance differences in children
Overdose Effects
- Supportive and symptomatic treatment
- Potential use of gastric lavage
- Enhancement of elimination rate with diuresis
- Impact of haemodialysis on plasma levels
Therapeutic Class
- Antifungal medications
- Treatment for subcutaneous and mycoses
Storage Conditions
- Dry place
- Protection from light and heat
- Child-proof storage