Premet 400 mg (Tablet)
Unit Price: ৳ 1.50 (100's pack: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Premier pharmaceuticals ltd |
Title
- Premet 400 mg Tablet
Categories
- Pharmaceuticals
- Medicines
- Antibiotics
- Antiparasitic Agents
- Amoebicides
- Antiprotozoal
Indications
- Prevention of post-operative infections due to anaerobic bacteria
- Treatment of septicaemia and bacteraemia
- Treatment of urogenital trichomoniasis
- Treatment of bacterial vaginosis
- Treatment of all forms of amoebiasis
- Treatment of giardiasis
- Treatment of acute ulcerative gingivitis
- Treatment of anaerobically infected leg ulcers and pressure sores
- Treatment of acute dental infections due to anaerobic organisms
- Prevention of antibiotic-associated pseudomembranous colitis
Pharmacology
- Member of the imidazole class of antibacterial drug
- Classified therapeutically as an antiprotozoal agent
- Interacts with DNA and gives bactericidal action
Mode of Action
- 5-nitro group of Metronidazole is reduced by anaerobes metabolically
Dosage and Administration
- Dose varies for trichomoniasis, intestinal amoebiasis, extra-intestinal & asymptomatic amoebiasis, giardiasis, acute ulcerative gingivitis, acute dental infections, bacterial vaginosis, leg ulcers and pressure sores, anaerobic infections, and surgical prophylaxis
Interaction
- Disulfiram may lead to psychotic reactions
- Alcohol consumption during therapy can cause a disulfiram-like reaction
- Interactions with oral anticoagulant therapy, lithium, cyclosporin, phenytoin or phenobarbital, 5-fluorouracil, and busulfan
Contraindications
- Hypersensitivity to Metronidazole or other Nitroimidazole derivatives
Side Effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy & Lactation
- FDA Pregnancy Category B
- Excreted in human milk
- Use during pregnancy only if clearly needed
- Caution when administered to nursing women
Precautions & Warnings
- Regular hematological tests recommended for prolonged administration
- Caution in patients with hepatic encephalopathy
- May darken urine
Use in Special Populations
- Reduced dosage for hepatic impairment
- No dosage reduction needed for renal impairment
- Caution during haemodialysis and peritoneal dialysis
Overdose Effects
- Reported symptoms include vomiting, ataxia, and slight disorientation
- No specific antidote
- Symptomatic and supportive treatment recommended
Therapeutic Class
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
Storage Conditions
- Store below 30°C
- Keep protected from light
- Keep out of reach of children
- Do not use after expiry date
Common Questions
- What is Premet 400 mg Tablet?
- Uses of Premet 400 mg Tablet
- Side effects of Premet 400 mg Tablet
- Time to see improvement of conditions
- Contraindications to Premet 400 mg Tablet
- Safety during pregnancy
- Effects of taking more than the recommended dose
Quick Tips
- Treats infections caused by bacteria and parasites
- May cause side effects like nausea and a metallic taste in the mouth
- High doses or prolonged use increases the risk of side effects
- Avoid alcohol consumption during and after treatment
- Inform doctor if you have liver disease