Flubest 50 mg/5 ml (Powder for Suspension)

35 ml bottle: ৳ 78.23

Medicine Details

Title

  • Flubest Antifungal Medicine

Categories

  • Medicine
  • Antifungal
  • Therapeutic

Description

  • Flubest is an antifungal medicine used to treat various fungal infections in different parts of the body, including vaginal candidiasis, oropharyngeal candidiasis, oesophageal candidiasis, tinea infections, kerion, pityriasis versicolor, onychomycosis, invasive candidal infections, cryptococcal infections, prevention of fungal infections, and more.

Color Options

  • White

Dimensions

  • 5x5x10 cm

Packaging

  • Box

Dosage Form

  • Tablet
  • Oral Suspension

Strength

  • 150 mg
  • 200 mg
  • 400 mg

Active Ingredient

  • Fluconazole

Pharmacological Action

  • Inhibition of fungal cytochrome P-450 dependent enzymes
  • Synthesis of ergosterol

Dosage Instructions

  • Dosage varies based on the type of infection and patient age. It ranges from a single 150 mg dose to weekly doses over several months for certain conditions.

Administration

  • Oral
  • Intravenous

Age Group

  • Adults
  • Children over 1 year

Special Population Use

  • Elderly
  • Renal Impairment
  • Lactating Mothers

Interaction with Other Drugs

  • Warfarin
  • Sulphonylureas
  • Hydrochlorothiazide
  • Phenytoin
  • Rifampicin
  • Oral contraceptives
  • Cyclosporin
  • Theophylline

Contraindications

  • Known hypersensitivity to Fluconazole or related triazole compounds

Side Effects

  • Nausea
  • Abdominal discomfort
  • Diarrhoea
  • Flatulence
  • Rash
  • Anaphylaxis

Pregnancy & Lactation

  • Not recommended for use during pregnancy or in women of childbearing potential without adequate contraception due to adverse fetal effects seen in animals at high doses

Precautions & Warnings

  • Abnormalities in hepatic, renal, and hematological function tests observed
  • Rare cases of severe cutaneous reactions
  • Discontinue therapy if rash develops in superficial or systemic fungal infections
  • Not recommended for use during lactation

Pediatric Uses

  • Dosage adjustments based on renal impairment in children

Overdose Effects

  • Supportive and symptomatic treatment
  • Forced volume diuresis may increase elimination rate
  • Haemodialysis decreases plasma levels by approximately 50%

Therapeutic Class

  • Drugs for subcutaneous and mycoses

Storage Conditions

  • Store in a dry place, away from light and heat, and out of the reach of children

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