Aid SR 100 mg (Tablet (Sustained Release))

Unit Price: ৳ 3.00 (100's pack: ৳ 300.00)

Medicine Details

Category	Details
Generic	Diclofenac sodium
Company	Premier pharmaceuticals ltd
Also available as	Aid tr 100 mg capsule Aid 50 mg tablet

Indications

Inflammatory and degenerative forms of rheumatism
Chronic involutive polyarthritis
Ankylosing spondylarthritis
Osteoarthritis
Spondylarthroses
Acute gout
Peri-articular rheumatic disorders
Sprain
Bruises
Dislocations
Fractures
Softtissue injuries
Surgical interventions
Primary dysmenorrhoea
Episiotomy
Adnexitis
Endometritis
Parametritis
Salpingitis
Mastitis
Pre-operative medication for the prevention of pain
Inflammation
Swelling
Post-operative and post-traumatic pain
Prevention of pain and treatment of inflammation and swelling
Urogenital tract
Renal and biliary colic

Pharmacology

Potent non-steroidal anti-inflammatory drug (NSAID) with pronounced anti-rheumatic, anti-inflammatory, analgesic and antipyretic properties. It has some uricosuric effect. Inhibits prostaglandin biosynthesis which plays a major role in causing inflammation, pain and fever. Rapid and complete absorption from the gastro-intestinal tract when taken with or after meal. Metabolized in the liver and undergoes first pass metabolism.

Dosage & Administration

Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food
1 tablet daily, taken whole with liquid, preferably at meal times. If necessary, the daily dose can be increased to 150 mg by supplementation with conventional tablets
The recommended daily dosage for Diclofenac Dispersible Tablet is 2-3 tablets and the maximum daily dose is 150 mg. In milder cases, 2 tablets of Diclofenac DT per day are sufficient. Diclofenac DT should preferably be taken before meals
One capsule daily. Diclofenac TR should be taken preferably after mealtimes
For adults: 50 mg suppository 2-3 times daily. Maximum daily dose is 150 mg
For adults the usual dose is 1 ampoule daily. In serious cases this dose may be increased up to 2 ampoules daily
For external use only. Depending on the size of area to be treated, 2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily. To the affected area gel should be rubbed in lightly. This gel may also be given in addition to further treatment with other dosage forms of Diclofenac

Interaction

May increase plasma concentrations of lithium and digoxin
Increased risk of haemorrhage with the combined use of diclofenac and anticoagulant therapy
Can be given together with oral antidiabetic agents without influencing their clinical effect
Cases of nephrotoxicity have been reported in patients receiving cyclosporin and diclofenac concomitantly
Cases of serious toxicity have been reported when methotrexate and NSAIDs are given within 24 hours of each other
Convulsions may occur due to an interaction between quinolones and NSAIDs. Therefore, caution should be exercised when considering concomitant therapy of NSAID and quinolones
Co-administration of diclofenac with other systemic NSAIDs and steroids may increase the frequency of unwanted effects. With aspirin, the plasma levels of each is lowered, although no clinical significance is known

Contraindications

Hypersensitive to any ingredient of the products. Peptic ulcer, hypersensitivity to Diclofenac like other non-steroid anti-inflammatory agents, Diclofenac is also contra-indicated in asthmatic patient in whom attack with asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or by other drugs with prostaglandin synthetase inhibitor. This Gel should not be used under occlusive airtight dressings.

Side Effects

Epigastric pain
Eructation
Nausea
Diarrhea
Dizziness
Headache
Peripheral edema
Skin reactions
Rash
Eczema
Local irritation and reddening of the skin
Skin rash

Pregnancy & Lactation

During pregnancy, Diclofenac should be employed only for compelling reasons. The lowest effective dose should be used. These types of drugs are not recommended during the first trimester of pregnancy. In view of insufficient clinical data, Diclofenac Sodium Gel is not recommended during pregnancy. A very insignificant quantity of Diclofenac may be detected in breast milk but no undesirable effects on the infant to be expected.

Precautions & Warnings

In rare instances where peptic ulceration or gastrointestinal bleeding occurs in patients under treatment with Aid SR. In patients with advanced age should be kept under close observation. Aid SR Gel should not be allowed to come in contact with the eyes or mucus membranes, after application the hands should be washed properly and not to be taken by mouth.

Therapeutic Class

Drugs for Osteoarthritis
Drugs used for Rheumatoid Arthritis
Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Store in a cool and dry place, protected from light. Store below 30°C. Keep out of the reach of children.