Benidon 10 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Benham pharmaceuticals ltd |
| Also available as |
Title
- Benidon 10 mg Tablet
Categories
- Medicine
- Pharmaceuticals
Indications
- Dyspeptic symptom complex
- Delayed gastric emptying
- Gastroesophageal reflux
- Esophagitis
- Acute nausea and vomiting
- Parkinson's disease
- Radiological studies
Pharmacology
- Dopamine antagonist
- ChemoreceptorTrigger Zone (CTZ) blocker
- Gastroprokinetic action
- Gastrointestinal motility regulation
- Gastric emptying facilitation
- Esophageal peristalsis enhancement
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Maximum dose for adults is 80 mg daily
- Maximum period of treatment for acute nausea and vomiting is 12 weeks
Interaction
- Concomitant administration of anticholinergic drugs may antagonize the effect
- Antacids and antisecretory drugs should not be given simultaneously
- Main metabolic pathway is through CYP3A4
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Use during first trimester justified by therapeutic benefit
- Excreted in breast milk at 4 times lower concentrations than in plasma
- Nursing not recommended unless benefits outweigh potential risk
Precautions & Warnings
- Absolute caution in the case of children
- Increased risk of extra-pyramidal reactions in young children
- Use with caution in patients with hepatic impairment
Use in Special Populations
- Great caution and close medical supervision for infants under 1 year of age
- Caution in patients with hepatic impairment
- Dosing frequency should be reduced in patients with severe renal insufficiency
Overdose Effects
- Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
- Administration of activated charcoal and close observation recommended
- Anticholinergic drugs may be helpful in controlling extrapyramidal reactions
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure image available
Common Questions
- Used to treat nausea and vomiting
- Helps relieve indigestion
- May cause dizziness and sleepiness
- Avoid consuming alcohol while taking this medication