Bioxon 500 mg/vial (IM Injection)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Benham pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic. It has potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. Like other cephalosporins and penicillins, Ceftriaxone kills bacteria by interfering with the synthesis of the bacterial cell wall.
Dosage
- Adult: 1 to 2 gm by intravenous or intramuscular administration once a day
- Infants and Children (01 month or older): 50 to 75 mg/kg intravenous or intramuscular administration once a day
Administration
- Intramuscular Injection
- Intravenous Injection
Interaction
No drug interactions have been reported.
Contraindications
Ceftriaxone should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics.
Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Pruritus
- Urticaria
- Erythema multiforme
- Thrombocytopenia
- Leucopenia
- Anemia
- Neutropenia
- Elevations of SGOT or SGPT
- Bilirubinemia
- Nervousness
- Confusion
Pregnancy & Lactation
Its safety in human pregnancy has not been established. Caution should be exercised when Ceftriaxone is administered to a lactating mother.
Precautions & Warnings
- Anaphylactic shock
- Shadows suggesting sludge in the gallbladder
- Blood picture should be checked at regular intervals
Use in Special Populations
Bioxon must not be given to neonates if the neonate is premature and newborn (up to 28 days of age).
Overdose Effects
There is no specific antidote. Treatment of overdosage should be symptomatic.
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Vial store in a cool, dry place (below 30° C), away from light & moisture. Keep out of the reach of children.