Esoben 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Benham pharmaceuticals ltd
Also available as
Esoben 40 mg capsule Esoben 20 mg tablet Esoben 40 mg tablet

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment for Zollinger-Ellison Syndrome
  • Management of Acid-related Dyspepsia
  • Treatment for Duodenal & Gastric ulcers

Pharmacology

  • Function: Proton pump inhibitor for suppressing gastric acid secretion
  • Absorption: Enteric-coated pellet formulation with peak plasma levels after oral administration
  • Distribution: 97% plasma protein bound
  • Metabolism: Extensively metabolized in the liver by cytochrome P450 enzymes
  • Excretion: Plasma elimination half-life of approximately 1–1.5 hours
  • Combination Therapy: Used in combination with antimicrobials for H. pylori eradication

Dosage

  • Oral dosage form for various indications
  • IV Injection and Infusion for different patient groups

Administration

  • Tablet or capsule: Swallowed whole, taken one hour before a meal
  • Oral Suspension: Instructions for mixing with water and administration through a nasogastric or gastric tube
  • IV Injection: Preparation and administration guidelines

Interactions

  • Metabolism: Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Effect on Other Drugs: Potential interference with drugs where gastric pH is important for bioavailability

Contraindications

  • Known hypersensitivity to the formulation

Side Effects

  • Frequently occurring adverse events such as headache, diarrhea, nausea, etc.

Pregnancy & Lactation

  • Studies and Recommendations: No adequate and well-controlled studies in pregnant women, breastfeeding caution

Precautions & Warnings

  • General: Symptomatic response does not preclude the presence of gastric malignancy
  • Information for patients: Guidelines for swallowing capsules and use of antacids

Use in Special Populations

  • Paediatric Use: Safety and effectiveness not established
  • Geriatric Use: No observed differences in safety and efficacy
  • Hepatic Insufficiency: Dosage adjustment recommendations for severe insufficiency
  • Renal Insufficiency: No expected alterations in pharmacokinetics

Overdose Effects

  • Toxicity: Lethal dose observed in rats
  • Symptoms: Reduced motor activity, changes in respiratory frequency, tremor, etc.

Storage Conditions

  • Temperature and Protection: Store at a temperature not exceeding 30°C, protect from light and moisture

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Structure: Chemical structure information

Common Questions

  • Usage and effect explanations
  • Side effects information
  • Pregnancy and breastfeeding queries
  • Onset of action details
  • Quick Tips for usage

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