Esoben 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Esomeprazole
Company Benham pharmaceuticals ltd
Also available as
Esoben 20 mg capsule Esoben 20 mg tablet Esoben 40 mg tablet

Title

  • Esoben 40 mg Capsule

Categories

  • Medicine
  • Pharmacy
  • Health & Wellness

Description

  • A proton pump inhibitor for relieving symptoms associated with chronic heartburn, GERD, erosive esophagitis, and other gastric conditions
  • Used in combination with antibiotics for Helicobacter pylori eradication and for the management of Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal and gastric ulcers

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related dyspepsia
  • Treatment of duodenal and gastric ulcers

Pharmacology

  • DrugAction:
    • Suppression of gastric acid secretion
  • Absorption:
    • Peak plasma levels occur at approximately 1.5 hours after oral administration
    • Systemic bioavailability is approximately 90% at steady state
    • Plasma protein binding is constant over a specified concentration range
  • Metabolism:
    • Extensively metabolized in the liver by the cytochrome P450 enzyme system
  • Excretion:
    • Plasma elimination half-life is approximately 1–1.5 hours
    • Less than 1% of the parent drug is excreted in the urine

Dosage

  • Oral:
    • Dosage forms: 20 mg or 40 mg capsules
    • Healing of erosive esophagitis: 20 mg or 40 mg once daily for 4-8 weeks
    • Maintenance of healing of erosive esophagitis: 20 mg once daily
    • Symptomatic GERD: 20 mg once daily for 4 weeks
  • Iv:
    • Dosage forms: Injection or infusion
    • Dosage for adult patients (≥18 years): 20 mg or 40 mg once daily
    • Dosage for pediatric patients (1 month to <1 year): 0.5 mg/kg once daily

Administration

  • TabletOrCapsule: Swallowed whole and taken one hour before a meal
  • OralSuspension: Should be prepared and consumed within a specified timeframe
  • IvInjection: Administered intravenously over a period of at least 3 minutes

Interaction

  • Metabolism:
    • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • PotentialInterference:
    • May interfere with the absorption of certain drugs where gastric pH is an important determinant of bioavailability

Contraindications

  • Known hypersensitivity to any of the formulation

SideEffects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

PregnancyAndLactation

  • No adequate and well-controlled studies in pregnant women
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

PrecautionsAndWarnings

  • General: Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Administration: Emphasize the appropriate method of consuming the medication to patients

SpecialPopulations

  • PediatricUse: Safety and effectiveness not established
  • GeriatricUse: No overall differences in safety and efficacy observed between the elderly and younger individuals
  • HepaticInsufficiency: No dosage adjustment recommended for mild to moderate insufficiency
  • RenalInsufficiency: Pharmacokinetics not expected to be altered in patients with renal impairment

OverdoseEffects

  • Toxicity: Major signs of acute toxicity include reduced motor activity, tremor, and ataxia
  • Management: Symptomatic and supportive treatment is advised

StorageConditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

ChemicalStructure

  • MolecularFormula: C17H19N3O3S
  • Image: Chemical structure image URL

CommonQuestions

  • Uses: Treatment for GERD, ulcers, and conditions involving excessive stomach acid
  • SideEffects:
    • Headaches
    • Diarrhea
    • Nausea
    • Gas
    • Stomach pain
    • Constipation
    • Dry mouth
  • PregnancyAndBreastfeeding: Discuss potential risks and benefits with a healthcare provider
  • OnsetOfAction: Usually starts to work within a few hours of intake
  • QuickTips:
    • Esoben 40 mg Capsule is well-tolerated and provides long-term relief
    • Avoid eating late at night or before bedtime
    • Consult a doctor if persistent stomach symptoms occur
    • Long-term use may affect bone health and mineral levels
    • Promptly seek medical attention if signs of kidney problems arise

Related Brands