Esoben 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 6.00 (7 x 10: ৳ 420.00)

Strip Price: ৳ 60.00

Medicine Details

Category	Details
Generic	Esomeprazole
Company	Benham pharmaceuticals ltd
Also available as	Esoben 20 mg capsule Esoben 40 mg capsule Esoben 40 mg tablet

Title

Esoben 20 mg Tablet

Description

Proton pump inhibitor for relieving chronic heartburn symptoms and other symptoms associated with GERD
Healing of erosive esophagitis
Maintenance of healing of erosive esophagitis
Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease in combination with amoxicillin and clarithromycin
Treatment of Zollinger-Ellison Syndrome
Management of Acid related Dyspepsia
Healing of Duodenal & Gastric ulcer

Dimensions

Tablet: Various sizes as per dosage

Color options

White

Functions

Reduces gastric acid secretion
Promotes healing of esophagitis
Eradicates H. pylori infection
Relieves symptoms of GERD
Controls acid for a specific duration
Prevents rebleeding of gastric or duodenal ulcers
Inhibits absorption of certain drugs

Materials

Enteric-coated pellet formulation of esomeprazole magnesium

Technical specifications

Absorption: Peak plasma levels occur at approximately 1.5 hours after oral administration
Distribution: 97% bound to plasma proteins with a constant distribution range
Metabolism: Extensive metabolism in the liver by cytochrome P450 (CYP) enzymes
Excretion: Plasma elimination half-life of approximately 1–1.5 hours with less than 1% excreted in urine

Usability features

Dosage Form:
- Tablet
- Capsule
- Oral Suspension
- IV Injection
- IV Infusion
Administration:
- Swallowed whole with water
- Can be mixed with food or drink for easier swallowing

Dosage

Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
Maintenance of Healing of Erosive Esophagitis: 20 mg Once Daily
Symptomatic GERD: 20 mg Once Daily for 4 Weeks
Helicobacter Pylori Eradication: Triple Therapy for 10 days
Zollinger-Ellison Syndrome: 20-80 mg Once Daily
Acid-related Dyspepsia: 20-40 mg Once Daily for 2-4 weeks
Duodenal Ulcer: 20 mg Once Daily for 2-4 weeks
Gastric Ulcer: 20-40 mg Once Daily for 4-8 weeks
IV Injection or Infusion for different scenarios and patient age groups

Interaction

Metabolized in the liver by CYP2C19 and CYP3A4
Unlikely to inhibit various CYP enzymes
May interfere with absorption of certain drugs
No clinically significant interactions with specific drugs

Contraindications

Known hypersensitivity to any of the formulation

Side effects

Headache
Diarrhoea
Nausea
Flatulence
Abdominal pain
Constipation
Dry mouth

Pregnancy and lactation

Pregnancy: No adequate and well-controlled studies in pregnant women
Lactation: Excretion in milk not studied, breastfeeding should be discontinued if essential

Precautions and warnings

General: Symptomatic response does not preclude presence of gastric malignancy
Information for Patients: Capsules should be taken at least one hour before meals
Antacids: May be used while taking the medication

Special populations use

Paediatric: Safety and effectiveness not established
Geriatric: No overall differences in safety and efficacy
Hepatic Insufficiency: No dosage adjustment recommended for mild to moderate insufficiency
Renal Insufficiency: Pharmacokinetics not expected to be altered

Overdose effects

A single oral dose at 510 mg/kg has been lethal to rats, no reports of overdose with the medication

Storage conditions

Store at a temperature not exceeding 30°C, protect from light and moisture, keep out of reach of children

Chemical structure

Molecular Formula: C17H19N3O3S
Chemical Structure: Image of chemical structure provided

Commonly asked questions about esoben 20mg tablet

Usage: Reduces stomach acid production to treat various digestive conditions
Side Effects: May include headaches, stomach-related issues
Pregnancy: Discuss potential risks with healthcare provider
Uptake Time: Usually starts working within a few hours