Esoben 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 6.00 (7 x 10: ৳ 420.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Benham pharmaceuticals ltd |
| Also available as |
Title
- Esoben 20 mg Tablet
Categories
- Medicine
- Pharmaceutical
Description
- Proton pump inhibitor for relieving chronic heartburn symptoms and other symptoms associated with GERD
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease in combination with amoxicillin and clarithromycin
- Treatment of Zollinger-Ellison Syndrome
- Management of Acid related Dyspepsia
- Healing of Duodenal & Gastric ulcer
Dimensions
- Tablet: Various sizes as per dosage
Color options
- White
Functions
- Reduces gastric acid secretion
- Promotes healing of esophagitis
- Eradicates H. pylori infection
- Relieves symptoms of GERD
- Controls acid for a specific duration
- Prevents rebleeding of gastric or duodenal ulcers
- Inhibits absorption of certain drugs
Materials
- Enteric-coated pellet formulation of esomeprazole magnesium
Technical specifications
- Absorption: Peak plasma levels occur at approximately 1.5 hours after oral administration
- Distribution: 97% bound to plasma proteins with a constant distribution range
- Metabolism: Extensive metabolism in the liver by cytochrome P450 (CYP) enzymes
- Excretion: Plasma elimination half-life of approximately 1–1.5 hours with less than 1% excreted in urine
Usability features
- Dosage Form:
- Tablet
- Capsule
- Oral Suspension
- IV Injection
- IV Infusion
- Administration:
- Swallowed whole with water
- Can be mixed with food or drink for easier swallowing
Dosage
- Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
- Maintenance of Healing of Erosive Esophagitis: 20 mg Once Daily
- Symptomatic GERD: 20 mg Once Daily for 4 Weeks
- Helicobacter Pylori Eradication: Triple Therapy for 10 days
- Zollinger-Ellison Syndrome: 20-80 mg Once Daily
- Acid-related Dyspepsia: 20-40 mg Once Daily for 2-4 weeks
- Duodenal Ulcer: 20 mg Once Daily for 2-4 weeks
- Gastric Ulcer: 20-40 mg Once Daily for 4-8 weeks
- IV Injection or Infusion for different scenarios and patient age groups
Interaction
- Metabolized in the liver by CYP2C19 and CYP3A4
- Unlikely to inhibit various CYP enzymes
- May interfere with absorption of certain drugs
- No clinically significant interactions with specific drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy and lactation
- Pregnancy: No adequate and well-controlled studies in pregnant women
- Lactation: Excretion in milk not studied, breastfeeding should be discontinued if essential
Precautions and warnings
- General: Symptomatic response does not preclude presence of gastric malignancy
- Information for Patients: Capsules should be taken at least one hour before meals
- Antacids: May be used while taking the medication
Special populations use
- Paediatric: Safety and effectiveness not established
- Geriatric: No overall differences in safety and efficacy
- Hepatic Insufficiency: No dosage adjustment recommended for mild to moderate insufficiency
- Renal Insufficiency: Pharmacokinetics not expected to be altered
Overdose effects
A single oral dose at 510 mg/kg has been lethal to rats, no reports of overdose with the medication
Storage conditions
Store at a temperature not exceeding 30°C, protect from light and moisture, keep out of reach of children
Chemical structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure: Image of chemical structure provided
Commonly asked questions about esoben 20mg tablet
- Usage: Reduces stomach acid production to treat various digestive conditions
- Side Effects: May include headaches, stomach-related issues
- Pregnancy: Discuss potential risks with healthcare provider
- Uptake Time: Usually starts working within a few hours