Losart 100 mg (Tablet)
Unit Price: ৳ 12.03 (3 x 10: ৳ 360.90)
Strip Price: ৳ 120.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Losartan potassium |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Hypertension
- Renal Protection in Type-2 Diabetic Patients with Proteinuria
Pharmacology
- Binds to AT1 receptor
- Reduces vasoconstriction
- Reduces aldosterone release
Dosage & Administration
- Usual starting and maintenance dose of 50 mg once daily
- Total daily dose ranges from 25 mg to 100 mg
- Lower starting dose for patients over 75 years
Interaction
- Rifampicin and fluconazole reduce levels of active metabolite
- Concomitant use of hydrochlorothiazide may lead to potentiation of antihypertensive effects
- Concomitant use of potassium-sparing diuretics may lead to increases in serum potassium
Contraindications
- Contraindicated in pregnant women
- Contraindicated in patients hypersensitive to any component
- Should not be administered with Aliskiren in patients with diabetes
Side Effects
- Dizziness
- Diarrhea
- Nasal congestion
- Cough
- Fatigue
- Edema
- Headache
Pregnancy & Lactation
- Pregnancy Category D
- Risk increases if administered during second or third trimesters
- Potential excretion in human milk
Precautions & Warnings
- Reduces fetal renal function
- Symptomatic hypotension may occur in intravascularly volume-depleted patients
- Significantly increased plasma concentration in cirrhotic patients
Use in Special Populations
- No initial dosage adjustment in patients with mild renal impairment
- Lower starting dose for patients with moderate to severe renal impairment
Therapeutic Class
- Angiotensin-II receptor blocker
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children