Esoben MUPS 20 mg (MUPS Tablet)
Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole mups preparation |
| Company | Benham pharmaceuticals ltd |
Title
- Esoben MUPS 20 mg Tablet
Categories
- Medicine
- Health
- Pharmaceutical
Description
- MUPS is abbreviation for Multiple-Unit Pellet System
- Ensures greater bioavailability
- Ensures uniform emptying of micro pellets from stomach into small intestine
- Facilitates rapid dissolution of enteric coating and drug release resulting in early Tmax and Cmax
- Ensures lesser possibility of dose dumping
- Combination of fast acting and sustained action
- Once daily dosing
- Ensures better and more uniform drug absorption
- Minimizes fluctuation in plasma concentration of drug
- Rapid and uniform gastric emptying
- Uniform drug dissolution of pellets in the gastrointestinal tract
- Consistent and controlled pharmacological action
- Reduction in inter- and intra-subject variability in drug absorption
Indications
- Gastro-esophageal Reflux Disease (GERD)
- Risk reduction in NSAID associated gastric ulcer
- H. pylori eradication (Triple therapy)
- Zollinger-Ellison syndrome and idiopathic hypersecretion
Composition
- 133.333 mg (15%w/w) of Esomeprazole enteric coated pellets equivalent to 20 mg Esomeprazole
- 266.67 mg (15% w/w) of Esomeprazole enteric coated pellets equivalent to 40 mg Esomeprazole
Pharmacology
- Inhibits gastric acid by blocking the hydrogen-potassium adenosine triphosphatase enzyme system
Dosage
- 40 mg once daily for 4 weeks (Adults)
- 20 mg once daily (Adults)
- 20 mg once daily for 4-8 weeks (Adults)
- 20 mg twice daily for 7 days (Adults)
- 40-80 mg twice daily (Adults)
- 10 mg once daily for 8 weeks (Children 1-11 years)
- 10 mg or 20 mg once daily for 8 weeks (Children 1-11 years)
Administration
- Tablets should be swallowed whole with liquid
- Can be dispersed in half a glass of non-carbonated water
Interaction
- Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
- No clinically relevant interactions with drugs metabolized by these CYP enzymes
- May interfere with the absorption of drugs where gastric pH is important
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- Caution advised
Precautions & Warnings
- Use carefully if the patient has severe liver dysfunction and severe renal impairment
- Slightly increases the risk of hip, wrist and spine fracture over a period of more than one year
Storage Conditions
- Store in a cool & dry place below 25°C
- Protect from light
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
Common Questions
- Multiple uses including treating GERD and ulcers
- Common side effects include headache, diarrhea, nausea
- Caution advised for pregnant and breastfeeding individuals