Fluderm 150 mg (Tablet)
Unit Price: ৳ 22.00 (1 x 10: ৳ 220.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluconazole |
| Company | Benham pharmaceuticals ltd |
| Also available as |
Indications
- Vaginal Candidiasis
- Oropharyngeal Candidiasis
- Oesophageal Candidiasis
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
- Kerion
- Pityriasis versicolor
Other Indications
- Onychomycosis
- Invasive candidal infections and cryptococcal infections (including meningitis)
- Prevention of cryptococcal meningitis
- Prevention of fungal infections in immunocompromised patients
- Systemic Candidiasis and Cryptococcal infection
- Fungal urinary tract infections
- Disseminated candidiasis
- Prophylaxis for fungal infection in neutropenic cancer patients
- Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis
Pharmacology
Fluconazole is a triazole antifungal agent. It is a potent inhibitor of fungal cytochrome P-450 dependent enzymes
Dosage & Administration
- Adults:
- Vaginal Candidiasis: 150 mg as a single dose
- Oropharyngeal Candidiasis: 200 mg in 1st day followed by 100 mg daily for 14 days
- Oesophageal Candidiasis: 200 mg in 1st day followed by 100 mg daily for 14-30 days
- Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea: 150 mg weekly for 4-6 weeks
- Kerion: 50 mg daily for 20 days
- Pityriasis versicolor: 400 mg as a single dose
- Onychomycosis: 150 mg weekly for 12 months
- Invasive candidal infections and cryptococcal infections (including meningitis): 400 mg on first day then 200-400 mg daily
- Children:
- In Superficial Candidiasis: 1-2 mg/kg daily
- In Systemic Candidiasis & Cryptococcal infection: 3-6 mg/kg daily
- Use in Specific Population:
- Elderly patient
- Renal Impairment
- Children
Interaction
- Warfarin
- Sulphonyl ureas
- Hydrochlorothiazide
- Phenytoin
- Rifampicin
- Oral contraceptives
- Cyclosporin
- Food
- Cimetidine
- Theophylline
Contraindications
- Known hypersensitivity to Fluconazole or related triazole compounds
Side Effects
- Nausea
- Abdominal discomfort
- Diarrhoea
- Flatulence
- Rash
- Anaphylaxis
Pregnancy & Lactation
Fluconazole adverse fetal effects seen in animals only at dose levels associated with maternal toxicity. Use not recommended in pregnancy or in women of childbearing potential unless adequate contraception is employed.
Precautions & Warnings
- Abnormalities of hepatic, renal, haematological and other biochemical function tests
- Hapatic necrosis
- Exfoliative cutaneous reactions
- Use during lactation
- Driving/Use of machinery
Use in Special Populations
- Elderly
- Renal impairment
Overdose Effects
In the event of overdosage, supportive measures and symptomatic treatment with gastric lavage if necessary may be adequate
Therapeutic Class
Drugs for subcutaneous and mycoses
Storage Conditions
Dry place away from light and heat, Keep out of the reach of children