Phydox 200 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Benham pharmaceuticals ltd |
| Also available as |
Title
Phydox Bronchodilator Medicine
Categories
- Medicine
- Respiratory Care
- Bronchodilator
- Methyl Xanthine Derivatives
Description
Phydox is a bronchodilator medicine used to treat bronchial asthma, bronchospasm, chronic obstructive pulmonary disease (COPD), and pulmonary disease with a spastic bronchial component. It contains Doxophylline, a novel bronchodilator that selectively inhibits phosphodiesterase 4, relaxes bronchial smooth muscle, and has a better safety profile than Theophylline. The dosage varies for elderly, adults, and children, and it should not be administered with other xanthine preparations. Contraindications include known hypersensitivity, acute myocardial infarction, hypotension, and lactation. Side effects may include nausea, vomiting, tachycardia, and insomnia. Use during pregnancy and lactation should be carefully evaluated. Precautions are advised for patients with various health conditions and concurrent administration of specific drugs.
Dimensions
N/A
Color Options
N/A
Functions
- Bronchodilation
- Phosphodiesterase 4 Inhibition
- Smooth Muscle Relaxation
Materials
Generic Drug
Technical Specifications
- Doxophylline Content: Varies with Dosage
- Pharmacological Class: Methyl Xanthine Derivative
Design Elements
N/A
Usability Features
- Prescription Only
- Dosage Variation for Different Age Groups
Indications
- Bronchial Asthma
- Bronchospasm
- Chronic Obstructive Pulmonary Disease (COPD)
- Pulmonary Disease with Spastic Bronchial Component
Pharmacology
Doxophylline selectively inhibits phosphodiesterase 4, relaxes the bronchial smooth muscle, and has decreased affinities toward adenosine A1 and A2 receptors. It is reported to inhibit platelet activating factor (PAF) and generation of leukotriene production.
Dosage & Administration
- Elderly: 200 mg tablet two or three times daily
- Adults: 400 mg tablet two or three times daily or as prescribed by the physician
- Children:
- >12 years of age: 10 ml syrup or 200 mg tablet two or three times daily
- 6-12 years of age: 6-9 mg/kg body weight two times daily
Interaction
- Incompatible Drugs:
- Other Xanthine Preparations
- Ephedrine
- Sympathomimetic Drugs
- Erythromycin
- TAO
- Lincomycin
- Clindamycin
- Allopurinol
- Cimetidine
- Influenza Vaccine
- Propranolol
- Phenytoin
- Other Anticonvulsants
- Caution with Caffeine: Limit consumption of beverages and food containing caffeine
Contraindications
- Hypersensitivity: Known Hypersensitivity to Doxophylline or Other Xanthine Derivatives
- Medical Conditions:
- Acute Myocardial Infarction
- Hypotension
- Lactation
Side Effects
- Nausea
- Vomiting
- Epigastric Pain
- Headache
- Irritability
- Insomnia
- Tachycardia
- Tachypnea
- Hyperglycemia
- Albuminuria
Pregnancy & Lactation
- Pregnancy: Use should be evaluated carefully on the basis of risk-benefit ratio
- Lactation: Contraindicated
Precautions & Warnings
- Monitoring: Blood levels monitoring recommended for factors affecting drug clearance
- Caution for Use in Patients with:
- Cardiac Disease
- Hypertension
- Chronic Corpulmonale
- Liver Disease
- Peptic Ulcer
- Renal Impairment
- Addiction Risk: No Risk of Addiction or Dependence
Overdose Effects
Severe Cardiac Arrhythmias, Tonic-Clonic Seizure
Therapeutic Class
Bronchodilator, Methyl Xanthine Derivatives
Storage Conditions
- Dry Place
- Away from Light and Heat
- Keep Out of Reach of Children
- Prescription Only