Midorest 7.5 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Midazolam
Company Benham pharmaceuticals ltd
Also available as
Midorest 15 mg tablet

Title

Midorest

Categories

  • Sleep Aid
  • Anxiolytic
  • Sedative
  • Hypnotic
  • Benzodiazepine

Description

Midorest is a sleep-inducing agent characterized by a rapid onset and short duration of action. It also exerts an anxiolytic, anticonvulsant and muscle-relaxant effect.

Indications

  • Short-term treatment of insomnia
  • Sedation in premedication before surgical or diagnostic procedures

Pharmacology

The actions of benzodiazepines such as midazolam are mediated through the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which is one of the major inhibitory neurotransmitters in the central nervous system.

DosageAndAdministration

  • Oral dosage for adults: 7.5-15 mg daily
  • Intravenous administration for endoscopic or cardiovascular procedures: In healthy adults, the initial dose is approximately 2.5 mg

Interactions

  • Enhances the central sedative effect of neuroleptics, tranquillizers, antidepressants, sleep-inducing drugs, analgesics, anaesthetics, antipsychotics, anxiolytics, antiepileptic drugs and sedative antihistamines

Contraindications

  • Severe respiratory insufficiency
  • Severe hepatic insufficiency
  • Myasthenia gravis
  • Sleep apnea syndrome
  • Known hypersensitivity to benzodiazepines or to any component of the product

SideEffects

  • Drowsiness during daytime
  • Confusion
  • Fatigue
  • Headache
  • Muscle weakness
  • Respiratory depression
  • Apnea
  • Variations in blood pressure and pulse rate

PregnancyAndLactation

Midazolam should be avoided during pregnancy unless there is no safer alternative. Since Midazolam passes into breast milk, it should not be administered to breast-feeding mothers.

PrecautionsAndWarnings

Midorest IV should be administered very slowly.

OverdoseEffects

  • Coma
  • Areflexia
  • Cardiorespiratory depression
  • Apnea

TherapeuticClass

  • Benzodiazepine hypnotics
  • Benzodiazepine sedatives

StorageConditions

Protect from light and moisture, store in cool and dry place. Keep out of the reach of children.

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