Gutfix 8 mcg (Capsule)
Unit Price: ৳ 15.00 (2 x 10: ৳ 300.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Lubiprostone |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Irritable Bowel Syndrome with Constipation (IBS-C)
- Chronic Idiopathic Constipation (CIC) in adults
- Opioid-Induced Constipation (OIC) in adult patients with chronic, non-cancer pain
Pharmacology
- Locally-acting chloride-channel activator
- Increases intestinal secretion
- Increases intestinal motility
- Aids the passage of stool
- Relieves symptoms associated with chronic constipation
Dosage & Administration
- Recommended dose for IBS-C: 8 mcg twice daily orally with food and water
- Recommended dose for chronic constipation and OIC: 24 mcg twice daily orally with food and water
- Dosage adjustment for hepatic impairment
Interaction
- Possible decrease in efficacy when used with diphenylheptane opioids
Contraindications
- Contraindicated in patients with known or suspected mechanical gastrointestinal obstruction
Side Effects
- Diarrhea
- Full or bloated feeling or pressure in the stomach
- Nausea
- Stomach pain
- Swelling of abdominal or stomach area
- Dyspnea
Pregnancy & Lactation
- Pregnancy category C
- Caution when administered to nursing women
- Infants should be monitored for diarrhea
Precautions & Warnings
- Nausea management with concomitant food administration
- Avoid in patients with severe diarrhea
- Thorough evaluation for mechanical gastrointestinal obstruction prior to therapy
Overdose Effects
- Adverse reactions may include nausea, diarrhea, vomiting, dizziness, headache, abdominal pain, flushing/hot flash, retching, dyspnea, pallor
Therapeutic Class
- Other laxative preparations
Storage Conditions
- Store between 15-30°C